Results 1 to 10 of about 104,554 (289)

Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis? [PDF]

Annals of Geriatric Medicine and Research, 2023
Background Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of metalloproteinases (TIMPs).
Bahar Bektan Kanat, Gulru Ulugerger Avci, Osman Faruk Bayramlar, Damla Unal, Ozge Sonmez, Ibrahim Murat Bolayirli, Alper Doventas, Deniz Suna Erdincler, Hakan Yavuzer   +8 more
doaj   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Echinoderms: Structure and Possible Functions [PDF]

Cells, 2021
Echinoderms are one of the most ancient groups of invertebrates. The study of their genomes has made it possible to conclude that these animals have a wide variety of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs ...
Igor Yu. Dolmatov, Vladimir A. Nizhnichenko, Lyudmila S. Dolmatova   +2 more
doaj   +2 more sources

Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9. [PDF]

Matrix Biol, 2023
Extracellular proteolysis and turnover are core processes of tissue homeostasis. The predominant matrix-degrading enzymes are members of the Matrix Metalloproteinase (MMP) family. MMPs extensively degrade core matrix components in addition to processing a range of other factors in the extracellular, plasma membrane, and intracellular compartments.
Coates-Park S, Lazaroff C, Gurung S, Rich J, Colladay A, O'Neill M, Butler GS, Overall CM, Stetler-Stevenson WG, Peeney D.   +9 more
europepmc   +3 more sources

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity [PDF]

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021
Objectives: To study the association of Tissue inhibitors of matrix metalloproteinases (TIMP) levels with tuberculosis-diabetes comorbidity (TB-DM) comorbidity at baseline and in response to anti-TB treatment (ATT).
Nathella Pavan Kumar, Kadar Moideen, Vijay Viswanathan, Shanmugam Sivakumar, Syed Hissar, Hardy Kornfeld, Subash Babu   +6 more
doaj   +2 more sources

Tissue inhibitors of metalloproteinases. [PDF]

Genome Biol, 2011
Orchestration of the growth and remodeling of tissues and responses of cells to their extracellular environment is mediated by metalloproteinases of the Metzincin clan. This group of proteins comprises several families of endopeptidases in which a zinc atom is liganded at the catalytic site to three histidine residues and an invariant methionine ...
Murphy G.
europepmc   +4 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Are Potential Biomarkers of Pulmonary and Extra-Pulmonary Tuberculosis [PDF]

Frontiers in Immunology, 2020
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) are potential regulators of tuberculosis (TB) pathology. Whether they are candidates for non-sputum-based biomarkers for pulmonary TB (PTB) and extra-pulmonary TB (EPTB ...
Gokul Raj Kathamuthu, Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Dina Nair, Vaithilingam V. Banurekha, Rathinam Sridhar, Dhanaraj Baskaran, Subash Babu, Subash Babu   +9 more
doaj   +2 more sources

Circulating matrix metalloproteinases and tissue inhibitors of metalloproteinases in cardiac amyloidosis. [PDF]

J Am Heart Assoc, 2013
Background Cardiac amyloidosis due to amyloid fibril deposition in the heart results in cardiomyopathy ( CMP ) with heart failure ( HF ) and/or conduction disturbances. Immunoglobulin light chain–related CMP ( AL
Tanaka K, Essick EE, Doros G, Tanriverdi K, Connors LH, Seldin DC, Sam F.   +6 more
europepmc   +4 more sources

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]

Iranian Journal of Otorhinolaryngology, 2019
Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk, Piotr Sawicki, Lukasz Szylberg, Magdalena Bodnar, Andrzej Marszalek   +4 more
doaj   +1 more source

Distinct Metalloproteinase Expression and Functions in Systemic Sclerosis and Fibrosis: What We Know and the Potential for Intervention

Frontiers in Physiology, 2021
Systemic sclerosis (SSc) is a chronic debilitating idiopathic disorder, characterized by deposition of excessive extracellular matrix (ECM) proteins such as collagen which leads to fibrosis of the skin and other internal organs.
Edwin Leong, Michael Bezuhly, Michael Bezuhly, Jean S. Marshall, Jean S. Marshall   +4 more
doaj   +1 more source

Time-dependent matrix metalloproteinases and tissue inhibitor of metalloproteinases expression change in fusarium solani keratitis [PDF]

International Journal of Ophthalmology, 2016
AIM: To investigate matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) expression during the progress of fusarium solani (F.solani) keratitis in a rat model.
Qian Li, Xin-Rui Gao, Hong-Ping Cui, Li-Li Lang, Xiu-Wen Xie, Qun Chen   +5 more
doaj   +1 more source