Results 211 to 220 of about 83,548 (314)

Pharmacokinetics and pharmacodynamics of low doses of recombinant tissue plasminogen activator to establish a model for biosimilarity comparisons. [PDF]

Res Pract Thromb Haemost
Derhaschnig U, Buchtele N, Steiner MM, Drucker C, Firbas C, Schörgenhofer C, Gelbenegger G, König F, Jilma B, Kovacevic Miljevic KD.   +9 more
europepmc   +1 more source

Multimorbidity in dementia: Current perspectives and future challenges

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract Multimorbidity—the co‐occurrence of two or more chronic health conditions—affects > 86% of people with dementia. It is associated with cognitive and functional decline, reduced health‐related quality of life, increased health‐care use, and higher mortality.
Lucy E. Stirland, Radmila Choate, Preeti Pushpalata Zanwar, Panpan Zhang, Tamlyn J Watermeyer, Martina Valletta, Mario Torso, Stefano Tamburin, Usman Saeed, Gerard R. Ridgway, Shirine Moukaled, Jay B. Lusk, Samantha M. Loi, Thomas J. Littlejohns, Elżbieta Kuźma, Sarah‐Naomi James, Giulia Grande, Isabelle F. Foote, Katheryn A. Q. Cousins, Joe Butler, Abrar AbuHamdia, Thiago J. Avelino‐Silva, Vidyani Suryadevara   +22 more
wiley   +1 more source

Conservative Treatment of Empyema Formation Following Intrathoracic Rib Fixation With Antibiotics and Tissue Plasminogen Activator/Dornase. [PDF]

J Med Cases
Malkoc A, Mamoun L, Vignaroli K, Gill H, Barmanwalla A, Phan A, Daoud A, Nguyen A, Woodward B.   +8 more
europepmc   +1 more source

Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection

Advanced NanoBiomed Research, Volume 5, Issue 8, August 2025.
This study explores Fc engineering to extend nanobody half‐lives in vivo. Herein, it is demonstrated that the circulation half‐life of Nanosota‐3A‐Fc, a novel nanobody with potent neutralizing activity against SARS‐CoV‐2 Omicron BA.1 variant, can be greatly prolonged by introducing M252Y/S254T/T256E (YTE) substitutions in the IgG1 Fc domain, which ...
Geetha Jyothi Vaskuri, Gang Ye, Fan Bu, Dong Yang, Colleen B. Jonsson, Hailey Turner‐Hubbard, Sydney Winecke, Alise Mendoza, Fang Li, Chalet Tan   +9 more
wiley   +1 more source

A novel technique for extensive submacular hemorrhage using high-dose tissue plasminogen activator. [PDF]

Indian J Ophthalmol
Chauhan K, Narayanan R.
europepmc   +1 more source

Intracellular distribution of tissue-type plasminogen activator in human melanoma cells.

, 1988
Tetsuhiro Sakai, Kiyotaka Okada, Hiroshi Bando, Hideharu Fukao, Shigeru Ueshima, Osamu Matsuo   +5 more
openalex   +2 more sources

Current Advancement and Patient Outcomes in Reperfusion Brain Injuries After Stroke: A Comparative Analysis of Thrombolysis and Thrombectomy

Brain and Behavior, Volume 15, Issue 8, August 2025.
The graphical abstract illustrates how stroke‐induced reperfusion mitigates the brain injury and induces progressive brain damage. Early therapeutic or surgical intervention can be very beneficial to reduce stroke‐reperfusion‐induced brain damage. ABSTRACT Background Stroke remains a leading cause of death and disability worldwide, with ischemic stroke
Olobatoke Tunde Ayomide, Vishal Chavda, Bipin Chaurasia, Esther Bassey, Kanishk Dang, Henry Demian Oyoyo, Jackson T. S. Cheung, Aruni Velalakan, Odemona Glory Toluwanibukun, Nazmin Ahmed   +9 more
wiley   +1 more source

Intravitreal tissue plasminogen activator in submacular haemorrhage

Indian Journal of Ophthalmology, 1999
Singh Preetam, Singh Ravijit, Kishore K, Vig Vipin, Singh Rajbir, Singh Balbir   +5 more
doaj  

Diagnostic value of tissue plasminogen activator-inhibitor complex in sepsis-induced liver injury: A single-center retrospective case-control study. [PDF]

World J Hepatol
Zhou Y, He LP, Qi YH, Huang Y, Hu BQ, Liu JL, Zeng QB, Song JC.   +7 more
europepmc   +1 more source

Metabolic fate of recombinant human tissue plasminogen activator(rt-PA). (2): Blood or plasma concentration, distribution, metabolism, excretion and accumulation in rats after repeated intravenous administration.

, 1988
Seiu IIDA, Masato IWAMOTO, Masayuki Suzuki, Noriko Hisanaga, Teiko KOMATSU   +4 more
openalex   +2 more sources