Results 221 to 230 of about 599,368 (371)

The Effect of Recombinant Tissue Plasminogen Activator (r-tPA) on Quantitation of Neutralising Anti-Streptokinase Antibodies

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2004
The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen.
Afshin Afshari R. Elizbeth Holme
doaj  

An antisense oligonucleotide targeting the heat‐shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by fibroblast activation and abnormal accumulation of extracellular matrix in the lungs. We previously demonstrated the importance of the heat shock protein αB‐crystallin (HSPB5) in TGF‐β1 profibrotic signalling, which suggests that HSPB5 could be a new ...
Pierre‐Marie Boutanquoi   +17 more
wiley   +1 more source

Cell Biology of Cancer Peritoneal Metastasis: Multiclonal Seeding and Peritoneal Tumor Microenvironment

open access: yesCancer Science, EarlyView.
We summarize recent findings on the cell biological aspects of peritoneal metastasis and potential therapeutic target molecules. We focus on the molecular mechanisms underlying cluster/spheroid formation in multiclonal peritoneal metastasis and cancer–stroma interactions within the peritoneal tumor microenvironment. ABSTRACT Peritoneal metastasis, also
Hideki Yamaguchi, Makoto Miyazaki
wiley   +1 more source

Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogs. [PDF]

open access: bronze, 1988
Tsunehiro Yasuda   +9 more
openalex   +1 more source

Permeable Lung Vasculature Creates Chemoresistant Endothelial Niche by Producing SERPINE1 at Breast Cancer Metastatic Sites

open access: yesCancer Science, EarlyView.
Vascular permeability is increased by lung metastasis, which correlates with YAP activation in ECs. Activated ECs provide SERPINE1 to neighboring cancer cells to promote chemoresistance and stemness. ABSTRACT Chemotherapy resistance remains a major obstacle for eradicating metastatic cancer cells in distant organs. We identified that endothelial cells (
Tsunaki Hongu   +7 more
wiley   +1 more source

Comparative properties of two clinical preparations of recombinant human tissue-type plasminogen activator in patients with acute myocardial infarction

open access: bronze, 1987
Harry D. Garabedian   +6 more
openalex   +1 more source

Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis

open access: yesThe Lancet, 2012
J. Wardlaw   +6 more
semanticscholar   +1 more source

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