Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source
Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu +7 more
wiley +1 more source
A meta-analysis on racial disparity in administration of tissue plasminogen activator (tPA) in stroke patients. [PDF]
Larik MO, Bhattarai P.
europepmc +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Plasma tissue plasminogen activator-inhibitor complex levels in acute myocardial infarction patients: an observational study. [PDF]
Feng YF +5 more
europepmc +1 more source
ABSTRACT Aims This study investigates the degree of the perceived risk of intravenous thrombolysis in acute cerebral infarction among surrogate decision‐makers and the factors influencing their propensity to make decisions about thrombolysis. Design An investigation was conducted on a cross‐sectional basis.
Jie Yu +5 more
wiley +1 more source
Tissue Plasminogen Activator in Acute Cardiac Arrest. [PDF]
Acharya I, DeBoer SR, Haas CJ.
europepmc +1 more source
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon +6 more
wiley +1 more source
Correction: Usefulness of carotid duplex ultrasonography in predicting residual large-vessel occlusions after intravenous recombinant tissue plasminogen activator therapy in patients with acute ischemic stroke. [PDF]
Kaburagi K +9 more
europepmc +1 more source
Development of Ultrasound Microbubbles and Phase Shift Microbubbles in Theranostics
Microbubbles have been originally designed for diagnostic applications. Over the years, microbubbles and phase shift microbubbles have been further developed for therapeutic indications. ABSTRACT Ultrasound is widely used for diagnostic imaging and therapy.
Emmanuelle J. Meuillet, Evan C. Unger
wiley +1 more source

