Results 71 to 80 of about 4,698,204 (249)

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism

Scientific Reports
Oral cancer stands as a prevalent maligancy worldwide; however, its therapeutic potential is limited by undesired effects and complications. As a medicinal edible fungus, Chaga mushroom (Inonotus obliquus) exhibits anticancer effects across diverse ...
Donghyeon Yeo, Yeo Gyun Yun, Seong-Jin Shin, Khandmaa Dashnyam, Anand Khurelbaatar, Jun Hee Lee, Hae-Won Kim   +6 more
doaj   +1 more source

A quantitative method to analyse F-actin distribution in cells

MethodsX, 2019
Changes in actin structure and distribution are involved in many cellular processes, such as differentiation, proliferation and migration. Differences in cell shape and size make the analysis of actin distribution difficult.
Jip Zonderland, Paul Wieringa, Lorenzo Moroni   +2 more
doaj   +1 more source

Skin tissue regeneration for burn injury

Stem cell research & therapeutics, 2019
The skin is the largest organ of the body, which meets the environment most directly. Thus, the skin is vulnerable to various damages, particularly burn injury.
A. Shpichka, D. Butnaru, E. Bezrukov, R. Sukhanov, A. Atala, V. Burdukovskii, Yuanyuan Zhang, P. Timashev   +7 more
semanticscholar   +1 more source

Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state

Science Advances, 2020
We report a biodegradable synthetic material that opens a door to repair damaged tissue via boosting cellular energy metabolism. Cellular bioenergetics (CBE) plays a critical role in tissue regeneration.
Haoming Liu, Yingying Du, J. St-Pierre, Mads S. Bergholt, H. Autefage, Jianglin Wang, Mingle Cai, Gaojie Yang, M. Stevens, Shengmin Zhang   +9 more
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Regulation of cardiac fibroblasts reprogramming into cardiomyocyte‐like cells with a cocktail of small molecule compounds

FEBS Open Bio
Myocardial infarction results in extensive cardiomyocyte apoptosis, leading to the formation of noncontractile scar tissue. Given the limited regenerative capacity of adult mammalian cardiomyocytes, direct reprogramming of cardiac fibroblasts (CFs) into ...
Danyang Chang, Changye Sun, Xiangqin Tian, Hongyin Liu, Yangyang Jia, Zhikun Guo   +5 more
doaj   +1 more source

Bone tissue regeneration: biology, strategies and interface studies

Progress in Biomaterials, 2019
Nowadays, bone diseases and defects as a result of trauma, cancers, infections and degenerative and inflammatory conditions are increasing. Consequently, bone repair and replacement have been developed with improvement of orthopedic technologies and ...
M. Ansari
semanticscholar   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration

Nature Communications, 2019
Implanted scaffolds with inductive niches can facilitate the recruitment and differentiation of host cells, thereby enhancing endogenous tissue regeneration.
Meifeng Zhu, Wen Li, Xianhao Dong, Xingyu Yuan, Adam C. Midgley, Hong Chang, Yuhao Wang, Haoyu Wang, Kai Wang, P. Ma, Hongjun Wang, D. Kong   +11 more
semanticscholar   +1 more source