Results 131 to 140 of about 22,741 (230)

Titin-Degradationsprodukte als potentielle Biomarker für Herzerkrankungen [PDF]

, 2016
Als serologische Biomarker für Herzerkrankungen kommen Fragmente des Titinproteins in Betracht. Ihre Identifikation erfolgte anhand von Herzgewebe gesunder (Donor) und herzinsuffizienter Probanden (DCM), wobei die Titindegradation mittels Trypsin ...
Roos, Viola Corinne
core  

Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere

The Journal of Clinical Investigation
Heterozygous (HET) truncating variant mutations in the TTN gene (TTNtvs), encoding the giant titin protein, are the most common genetic cause of dilated cardiomyopathy (DCM).
Dalma Kellermayer, Hedvig Tordai, Balázs Kiss, György Török, Dániel M. Péter, Alex Ali Sayour, Miklós Pólos, István Hartyánszky, Bálint Szilveszter, Siegfried Labeit, Ambrus Gángó, Gábor Bedics, Csaba Bödör, Tamás Radovits, Béla Merkely, Miklós S.Z. Kellermayer   +15 more
doaj   +1 more source

EFISIENSI PEMASARAN DAN PENDAPATAN USAHATANI RUMPUT LAUT [PDF]

, 2014
Rumput laut (seaweed culture) merupakan suatu komoditi budidaya perairan laut (aquaculture) yang berkembang saat ini. Algae merupakan bahasa latin rumput laut itu sendiri.
Afandi Rafsanjani, Titin Agustina, M.Sunarsih   +2 more
core  

Titin [PDF]

, 2020
openaire   +1 more source

Sacubitril/valsartan improves diastolic left ventricular stiffness with increased titin phosphorylation via cGMP-PKG activation in diabetic mice

Scientific Reports
Titin, a giant sarcomeric protein, regulates diastolic left ventricular (LV) passive stiffness as a molecular spring and could be a therapeutic target for diastolic dysfunction. Sacubitril/valsartan (Sac/Val), an angiotensin receptor neprilysin inhibitor,
Nozomi Furukawa, Hiroki Matsui, Hiroaki Sunaga, Kohzo Nagata, Masaaki Hirayama, Hideru Obinata, Tomoyuki Yokoyama, Kinji Ohno, Masahiko Kurabayashi, Norimichi Koitabashi   +9 more
doaj   +1 more source

Selective titin cleavage disrupts cardiac mechanical homeostasis to drive heart failure and fibrosis. [PDF]

Nat Cardiovasc Res
Freundt JK, Hartmann P, Loescher CM, Unger A, Koser F, Klotz AJ, Wildschütz L, Wachsmuth L, Hille S, Door MM, Helfen A, Holtmeier R, Faber C, Kirk JA, Hoerr V, Müller OJ, Linke WA.   +16 more
europepmc   +1 more source

TITIN Regulates Body Size via the JH-JHE Pathway in Honeybees (<i>Apis mellifera</i>). [PDF]

Int J Mol Sci
Qu X, Lu H, Zhang X, Xin L, Chen X.
europepmc   +1 more source

Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation. [PDF]

J Biol Chem
Pricolo MR, López-Unzu MA, Vicente N, Morales-López C, Huerta-López C, Pérez-Franco W, Dumitru AC, Peña-Peña J, Espinosa FM, Sanchez MI, Garcia R, Silva-Rojas R, Torres M, Herrero-Galán E, Alegre-Cebollada J.   +14 more
europepmc   +1 more source

Solution NMR study of the titin I-band IgI domain I82 shows unusual conformational dynamics. [PDF]

J Biomol NMR
Kelly CM, Abukar S, Gage MJ, Pfuhl M.
europepmc   +1 more source

Mending the Achilles heels of titin in cardiac and musculoskeletal disease. [PDF]

Biophys Rev
Martinez-Martin I, Silva-Rojas R, Alegre-Cebollada J.   +2 more
europepmc   +1 more source