Results 121 to 130 of about 22,741 (230)

RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Under normal conditions, RagD and mTORC1 respond to amino acid changes. Upon stimulation, active mTORC1 phosphorylates S6K, 4E‐BP1, and TFEB. In response to starvation, mTORC1 is inactive. Our data indicate that the RRAGD p.(Ser76Leu) variant maintains the phosphorylation of mTORC1 targets during starvation in T‐REx HeLa cells.
Anastasia Adella   +11 more
wiley   +1 more source

Pattern of titin disassembly during mitosis in NRVM. [PDF]

open access: yes, 2015
(A) Immunofluorescence staining of titin at both its N terminal (Z-disk, T12 antibody, red) and C terminal (M-line, M8 antibody, green) during mitosis. The clear alternating striation pattern of interphase cells (i) is disrupted starting from the end of ...
Mohammad A. M. Ali (754730)   +5 more
core   +1 more source

Disassembly of α-actinin precedes that of titin during mitosis. [PDF]

open access: yes, 2015
To delineate the possible sequential order of disassembly between α-actinin and titin during NRVM mitosis, triple staining of α-actinin (red), titin M8 epitope (green) and nuclear DNA (blue) was performed. (A) A typical prophase cell shows that α-actinin
Mohammad A. M. Ali (754730)   +5 more
core   +1 more source

Titin im Glatten Muskel in Embryo-Implantation und Angiogenese [PDF]

open access: yes, 2013
Das Muskelprotein Titin ist mit einem Molekulargewicht von bis zu 3700 kDa das größte bekannte Polypeptid. Es ist nach Aktin und Myosin das dritthäufigste Protein im quergestreiften Muskel. Titin integriert in die Z-Scheibe und die M-Bande und überspannt
Bergmann, Nora
core   +1 more source

Effect of L-Arginine on Titin Expression in Rat Soleus Muscle After Hindlimb Unloading

open access: yesFrontiers in Physiology, 2019
Nitric oxide (NO), produced by NO-synthases via L-arginine oxidation, is an essential trigger for signaling processes involved in structural and metabolic changes in muscle fibers.
Anna Ulanova   +8 more
doaj   +1 more source

The Mechanical Power of Titin Folding [PDF]

open access: yes, 2019
Summary: The delivery of mechanical power, a crucial component of animal motion, is constrained by the universal compromise between the force and the velocity of its constituent molecular systems.
Edward C. Eckels   +4 more
core   +1 more source

Titin regulation and maintenance in the cardiac sarcomere [PDF]

open access: yes, 2017
The giant myofilament protein titin is indispensable for the structural integrity and function of the sarcomere, however, little is known regarding the turnover of titin within the complex macromolecular sarcomere structure in contracting cardiomyocytes.
Cadar, Adrian Gabriel
core  

Analisis Omset Penjualan Keripik Pisang Agung UD. Nikmat Rasa Lumajang Tahun 2009-2013 [PDF]

open access: yes, 2015
Jenis penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif yang bertujuan untuk menganalisis omset penjualan keripik pisang agung UD. Nikmat Rasa Lumajang Tahun 2009-2013. Obyek dalam penelitian adalah UD.
Yunilawati, Sri Kantun, Titin Kartini
core  

Urinary Titin Level Is a Novel Marker of Severe Sarcopenia and Dynapenia: Shimane CoHRE Study

open access: yesJCSM Communications
Background In an aging society, it is important to intervene and prevent sarcopenia and dynapenia from an early stage. However, biochemical markers for screening sarcopenia and dynapenia have not yet been established.
Kanako Hara   +8 more
doaj   +1 more source

Titin: roles in cardiac function and diseases

open access: yesFrontiers in Physiology
The giant protein titin is an essential component of muscle sarcomeres. A single titin molecule spans half a sarcomere and mediates diverse functions along its length by virtue of its unique domains. The A-band of titin functions as a molecular blueprint
Dawson Stroik   +6 more
doaj   +1 more source

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