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Differential Expression Patterns of Toll-like Receptors in COVID-19 Patients
Frontiers in Bioscience-Landmark, 2023 Since Toll-like receptors (TLRs) recognize the earliest signs of infection or cell damage, they play fundamental roles in innate immunity. This review summarizes the numerous studies on the expression of TLRs in patients with Coronavirus disease 2019 ...
Nawon Lee, Ryeojin Ko, Soo Young Lee
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Filtered Kombucha Tea Rings the Bell for TLR2, TLR4, MYD88, and Dectin-1 in Mice Model of Colitis [PDF]
Research Journal of Pharmacognosy, 2020 Background and objectives: TLR2, TLR4, and Dectin-1 (Clec7) are pattern recognition receptors (PRRs) expressed by intestinal epithelia cells and MYD88 is a signaling molecule of TLR2 and TLR4.
Elaheh Mahmoudi* +2 more
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Association of single nucleotide polymorphisms of TLR2, TLR4 and TLR9 with atopic dermatitis
Медицинская иммунология, 2023 Toll-like receptors (TLRs) are the most studied among all Pattern Recognition Receptors, the main function of which is to initiate innate immune response by recognizing pathogen-associated molecular patterns of various microorganisms on the skin surface.
O. A. Svitich +5 more
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Gut Microbes, 2021 Vitamin D receptor (VDR) deficiency is associated with cancer, infection, and chronic inflammation. Prior research has demonstrated VDR regulation of bacteria; however, little is known regarding VDR and viruses. We hypothesize that VDR deficiency impacts
Jilei Zhang +3 more
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Clinical and immunological efficacy of interferonotherapy in rotavirus infection in infants
Журнал инфектологии, 2021 Purpose: to improve the complex therapy of rotavirus infection in infants by including interferon and to evaluate its clinical and immunological effectiveness.Materials and methods.
A. N. Os'kin +5 more
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Role of cytokine and Toll-like receptor genes in pathogenesis of inborn heart disease
Медицинская иммунология, 2022 Sporadic congenital heart disease (CHD) may result from immune disorders in the mother – embryo system and/or constitutional disorders in regulatory systems, including those associated with TLR receptors, cytokines and their receptors.
A. V. Shabaldin +2 more
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Journal of Animal Science and Technology, 2020 Polyinosinic:polycytidylic acid (poly[I:C]) can stimulate Toll-like receptor 3 (TLR3) signaling pathways. In this study, DF-1 cells were treated with poly(I:C) at various concentrations and time points to examine ...
Hyun-Jun Jang, Ki-Duk Song
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Role of Toll-like receptor gene polymorphism in pathogenesis of new coronavirus infection
Медицинская иммунология, 2023 The review article contains data from literature which concern the role of Toll-like receptors (TLRs), immune sensors that play a key role in the systemic response to both bacterial and viral infections, e.g., in pathogenesis of a new coronavirus ...
V. A. Beloglazov +3 more
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NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
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Inflammaging as the basis of age-associated diseases
Медицинская иммунология, 2020 Aging is one of the most complex biological phenomena that affects all human physiological systems, including the immune system. Immunosenescence is understood as structural and functional changes in both adaptive and innate immunity systems.
O. V. Artemyeva, L. V. Gankovskaya
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