Results 1 to 10 of about 300,160 (284)

Differential Expression Patterns of Toll-like Receptors in COVID-19 Patients

open access: yesFrontiers in Bioscience-Landmark, 2023
Since Toll-like receptors (TLRs) recognize the earliest signs of infection or cell damage, they play fundamental roles in innate immunity. This review summarizes the numerous studies on the expression of TLRs in patients with Coronavirus disease 2019 ...
Nawon Lee, Ryeojin Ko, Soo Young Lee
doaj   +1 more source

Association of single nucleotide polymorphisms of TLR2, TLR4 and TLR9 with atopic dermatitis

open access: yesМедицинская иммунология, 2023
Toll-like receptors (TLRs) are the most studied among all Pattern Recognition Receptors, the main function of which is to initiate innate immune response by recognizing pathogen-associated molecular patterns of various microorganisms on the skin surface.
O. A. Svitich   +5 more
doaj   +1 more source

Filtered Kombucha Tea Rings the Bell for TLR2, TLR4, MYD88, and Dectin-1 in Mice Model of Colitis [PDF]

open access: yesResearch Journal of Pharmacognosy, 2020
Background and objectives: TLR2, TLR4, and Dectin-1 (Clec7) are pattern recognition receptors (PRRs) expressed by intestinal epithelia cells and MYD88 is a signaling molecule of TLR2 and TLR4.
Elaheh Mahmoudi*   +2 more
doaj   +1 more source

Role of RP105 and A20 in negative regulation of toll-like receptor activity in fibrosis: potential targets for therapeutic intervention

open access: yesAIMS Allergy and Immunology, 2021
Toll-like receptors (TLRs) are essential defensive mediators implicated in immune diseases. Tight regulation of TLR function is indispensable to avoid the damaging effects of chronic signaling.
Swarna Bale   +2 more
doaj   +1 more source

Imbalance of the intestinal virome and altered viral-bacterial interactions caused by a conditional deletion of the vitamin D receptor

open access: yesGut Microbes, 2021
Vitamin D receptor (VDR) deficiency is associated with cancer, infection, and chronic inflammation. Prior research has demonstrated VDR regulation of bacteria; however, little is known regarding VDR and viruses. We hypothesize that VDR deficiency impacts
Jilei Zhang   +3 more
doaj   +1 more source

Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides [PDF]

open access: yes, 2008
While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Dan, Jennifer M.   +3 more
core   +9 more sources

Clinical and immunological efficacy of interferonotherapy in rotavirus infection in infants

open access: yesЖурнал инфектологии, 2021
Purpose: to improve the complex therapy of rotavirus infection in infants by including interferon and to evaluate its clinical and immunological effectiveness.Materials and methods.
A. N. Os'kin   +5 more
doaj   +1 more source

Role of cytokine and Toll-like receptor genes in pathogenesis of inborn heart disease

open access: yesМедицинская иммунология, 2022
Sporadic congenital heart disease (CHD) may result from immune disorders in the mother – embryo system and/or constitutional disorders in regulatory systems, including those associated with TLR receptors, cytokines and their receptors.
A. V. Shabaldin   +2 more
doaj   +1 more source

Expression patterns of innate immunity-related genes in response to polyinosinic:polycytidylic acid (poly[I:C]) stimulation in DF-1 chicken fibroblast cells

open access: yesJournal of Animal Science and Technology, 2020
Polyinosinic:polycytidylic acid (poly[I:C]) can stimulate Toll-like receptor 3 (TLR3) signaling pathways. In this study, DF-1 cells were treated with poly(I:C) at various concentrations and time points to examine ...
Hyun-Jun Jang, Ki-Duk Song
doaj   +1 more source

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]

open access: yes, 2020
Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice   +7 more
core   +1 more source

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