Results 41 to 50 of about 183,650 (307)

TLRs in pulmonary diseases

open access: yesLife Sciences, 2019
Toll-like receptors (TLRs) comprise a clan of proteins involved in identification and triggering a suitable response against pathogenic attacks. As lung is steadily exposed to multiple infectious agents, antigens and host-derived danger signals, the inhabiting stromal and myeloid cells of the lung express an aggregate of TLRs which perceive the ...
Arora, Shweta   +10 more
openaire   +2 more sources

Genetic polymorphism Arg753Gln of TLR-2, Leu412Phe of TLR-3, Asp299Gly of TLR-4 in patients with influenza and influenza-associated pneumonia [PDF]

open access: yes, 2019
The aim of the research is to study the prevalence and to determine the prognostic significance of polymorphism ARG753GLN of the TLR-2 gene, Leu412Phe of TLR-3, Asp299Gly of TLR-4 in influenza.
Pryimenko, N. O.   +11 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Postnatal gelişim sürecindeki sıçanların akciğerinde Toll-like reseptörlerinin (TLR-2, TLR-4, TLR-5 ve TLR-9) lokalizasyonları ve ekspresyonları

open access: yes, 2016
OBJECTIVE: Toll-like receptors (TLRs) are the transmembrane proteins, which recognize highly conserved structural motifs known as pathogen-associated microbial patterns (PAMPs), which are exclusively expressed by bacterial, fungal and viral ...
LİMAN, Narin, ALAN, Emel
core   +2 more sources

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez   +12 more
wiley   +1 more source

TLR Genotypes

open access: yes, 2017
TLR genotypes for each animal included in the analysis. Haplotype codes correspond to sequences provided in the archive "TLR inferred haplotype sequences.zip", also associated with this ...
Catherine E. Grueber (136239)   +11 more
core   +1 more source

How “Green” is Your Functional Material? Assessing Environmental Impacts of Multi‐Step Synthetic Protocols in Material Sciences at Various Technology Levels

open access: yesAdvanced Materials, EarlyView.
Environmental Synthesis Radar (ESR) evaluates the environmental impact of (early‐stage) multi‐step chemical syntheses, providing a holistic view by using 18 midpoint impact categories. Unlike conventional life‐cycle assessment (LCA) approaches, ESR reveals three complementary metrics: overall impact Vtotal, environmental hotspots VEF, and critical ...
Laura Plein   +8 more
wiley   +1 more source

Common variants in toll-like receptor family genes and risk of gastric cancer: a systematic review and meta-analysis

open access: yesFrontiers in Genetics, 2023
Background: An increasing number of studies have suggested the relationship between single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes and gastric cancer (GC) susceptibility; however, the available evidence is contradictory.
Ayoub Al Othaim   +8 more
doaj   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

open access: yesAdvanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo   +9 more
wiley   +1 more source

TLRs toll for Tregs [PDF]

open access: yesJournal of Leukocyte Biology, 2019
Abstract Discussion on TLR3 triggering in CD4 T cells induces IFN beta and IL10-producing iTregs that suppress food allergy.
openaire   +3 more sources

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