Results 141 to 150 of about 17,805,524 (287)
, 2018 The aim of the research is to study the efficacy of influenza vaccination in individuals with polymorphism Arg753Gln of TLR-2 gene, Leu412Phe of TLR-3 gene, and Asp299Gly of TLR-4 gene. Materials and methods.
Pryimenko, N. O. +2 more
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Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
BMEMat, EarlyView.This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Targeting dendritic cells with TLR-2 ligand-coated nanoparticles loaded with Mycobacterium tuberculosis epitope induce antituberculosis immunity. [PDF]
J Biol Chem, 2022 Kumar Das D +11 more
europepmc +1 more source
, 2006 La activación de los receptores tipo Toll (TLRs) se asocia estrechamente con la inducción de la expresión génica proinflamatoria; sin embargo, también se ha demostrado que la expresión de muchos otros genes, incluidos los propios genes TLR, se modula ...
Nhu, Quan M +2 more
core +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
BMEMat, EarlyView.This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
支气管肺泡灌洗液及血清NF-κB、TLR-2、TLR-4、 TNF-α在肺炎诊断中的应用价值
Zhongguo shiyan zhenduanxue目的 探讨支气管肺泡灌洗液(BALF)及血清核转录因子-κB(NF-κB)、Toll样受体2(TLR-2)、Toll样受体4(TLR-4)、肿瘤坏死因子α(TNF-α)在肺炎诊断中的应用价值。方法 选取2023年1月—2024年3月于吉林大学第二医院就诊的57例肺炎患者纳入研究组，另取同期体检的健康者57例纳入对照组，均采集外周静脉血与肺泡灌洗液，检测NF-κB、TLR-2、TLR-4、TNF-α水平，采用Pearson相关性分析患者血清及BALF中NF-κB、TLR-2、TLR-4、TNF-α的相关性。
金美玉, 王冠, 林文婷, 吴艳峰
doaj
Gardnerella vaginalis induces matrix metalloproteinases in the cervicovaginal epithelium through TLR-2 activation. [PDF]
J Reprod Immunol, 2022 Gerson KD +5 more
europepmc +1 more source
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
The novel hyaluronic acid granular hydrogel attenuates osteoarthritis progression by inhibiting the TLR-2/NF-κB signaling pathway through suppressing cellular senescence. [PDF]
Bioeng Transl Med, 2023 Zhang C +7 more
europepmc +1 more source
TLR-9 Expression in Human Bronchial Epithelial Cells induced with Lipopolysaccharide
, 2010 The study conducted here was to investigate the gene and protein expression of Toll like receptor 9 when human bronchial epithelial cells were induced by lipopolysaccharide.
Sangeetha Dharmalingam +1 more
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