Results 131 to 140 of about 141,965 (208)

Features of toll-like receptor genes (TLR-2, TLR-3, TLR-4 and TLR-6) polymorphism in open-angle glaucoma patients. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Shevchenko AV, Prokofiev VF, Konenkov VI, Chernykh VV, Trunov AN.   +4 more
europepmc   +1 more source

Association of TLR-2 Gene Polymorphisms with the Risk of Periodontitis: A Meta-Analysis. [PDF]

Dis Markers, 2020
Shan C, Aisaiti A, Wu ZP, Wang TT, Zhao J.   +4 more
europepmc   +1 more source

Physiology‐Guided Drug‐Coated Balloon Angioplasty: What We Know and What is Yet to be Understood

Catheterization and Cardiovascular Interventions, EarlyView.
Marco Frazzetto, Filippo Luca Gurgoglione, Bharat Khialani, Sandeep Basavarajaiah, Bernardo Cortese   +4 more
wiley   +1 more source

Fenfluramine in Rett syndrome: A multidimensional clinical study

Epilepsia Open, EarlyView.
Abstract Objective Rett syndrome (RTT) is a severe neurodevelopmental disorder frequently associated with drug‐resistant epilepsy, autonomic dysfunction, respiratory abnormalities, sleep disturbances, and behavioral impairment. Fenfluramine has shown efficacy in developmental and epileptic encephalopathies and may provide broader therapeutic benefits ...
Elena Gonzalez‐Alguacil, Nuria Lamagrande Casanova, Manuel Luján Bonete, David Mansilla Lozano, Juan José García Peñas, María Ballará Petitbó, Rocío Trincado Lamuño, Verónica Cantarín‐Extremera, Raquel Díaz Conejo, César Rodríguez Sánchez, Adrián García Ron, Víctor Soto Insuga   +11 more
wiley   +1 more source

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-<i>κ</i>B pathway. [PDF]

Front Pharmacol
Dong Z, Dong Z, Xu L, Zhang J, Li L, Wang R, Huang X, Zou Z.   +7 more
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Variants rs3804099 and rs3804100 in the TLR2 Gene Induce Different Profiles of TLR-2 Expression and Cytokines in Response to Spike of SARS-CoV-2. [PDF]

Int J Mol Sci
Flores-González J, Monroy-Rodríguez Z, Falfán-Valencia R, Buendía-Roldán I, Fricke-Galindo I, Hernández-Zenteno R, Herrera-Sicairos R, Chávez-Galán L, Pérez-Rubio G.   +8 more
europepmc   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source

Sulfate-Reducing Bacteria Induce Pro-Inflammatory TNF-α and iNOS via PI3K/Akt Pathway in a TLR 2-Dependent Manner. [PDF]

Microorganisms
Singh SB, Braun CA, Carroll-Portillo A, Coffman CN, Lin HC.   +4 more
europepmc   +1 more source

Upstream stimulatory factor 2 (USF2) induced upregulation of triggering receptor expressed on myeloid cells 1 (TREM1) promotes endometritis by regulating toll-like receptor (TLR) 2/4-nuclear factor-kappaB (NF-κB) signaling pathway. [PDF]

Bioengineered, 2022
Zhang M, Yin C, Chen Y, Wang J, Jiang J.
europepmc   +1 more source