Results 111 to 120 of about 137,836 (151)
Defective MyD88 and IRAK4 but not TLR-2 expression in HIV+ individuals with latent tuberculosis infection. [PDF]
Cytokine, 2018 Devalraju KP +7 more
europepmc +1 more source
TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection. [PDF]
Front Immunol, 2019 Kuriakose S +5 more
europepmc +1 more source
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Allergy: European Journal of Allergy and Clinical Immunology, 2009
Background: In many patients with atopic dermatitis (AD), the disease is complicated by their enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus. The pattern recognition receptor toll‐like receptor (TLR)‐2 recognizes components of S.
M, Niebuhr +3 more
exaly +3 more sources
Background: In many patients with atopic dermatitis (AD), the disease is complicated by their enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus. The pattern recognition receptor toll‐like receptor (TLR)‐2 recognizes components of S.
M, Niebuhr +3 more
exaly +3 more sources
Shock, 2009
Ischemia-reperfusion (I/R) activates innate immunity involving Toll-like receptor (TLR) 2 and TLR-4 signaling. Leukocyte migration and vascular permeability contribute to postischemic tissue damage. We hypothesized that TLR-2 and TLR-4 directly mediate leukocyte migration and vascular permeability during I/R.
Alexander Georg, Khandoga +3 more
openaire +2 more sources
Ischemia-reperfusion (I/R) activates innate immunity involving Toll-like receptor (TLR) 2 and TLR-4 signaling. Leukocyte migration and vascular permeability contribute to postischemic tissue damage. We hypothesized that TLR-2 and TLR-4 directly mediate leukocyte migration and vascular permeability during I/R.
Alexander Georg, Khandoga +3 more
openaire +2 more sources
The effects of age on CD4+ T cell TLR-2 expression and TLR-2 mediated direct co-stimulation (122.6)
The Journal of Immunology, 2012Abstract Background: Functional Toll like receptors (TLR) are found on human T cells. Neonatal antigen presenting cells (APC) have altered responses to TLR ligands; it is unknown if neonatal CD4+ T cell TLR responses are comparable to adult. Objective: Comparison of TLR-2 expression and responsiveness to TLR-2 direct co-stimulation among
Christina Lancioni +4 more
openaire +1 more source
TLR-2 Germ Line Variants as a Risk for Obesity in Local Pakistani Population
Archives of Medical Research, 2022Obesity is increasing rapidly affecting half billion adult's population. Pathophysiology of obesity involves low grade inflammation sustained by Toll like receptor 2 (TLR-2) the innate immune adapters. This study was conducted for detection and association of TLR-2 gene mutations with obesity.In this case-control study 228 individuals with obesity and ...
Mehreen Shoukat +5 more
openaire +2 more sources
TLR‐2‐mediated cytokine and chemokine secretion in human keratinocytes
Experimental Dermatology, 2010Abstract: The human epidermis provides a first line of defense against exogenous pathogens. Resistance to bacterial skin infections, e.g. with Staphylococcus aureus (S. aureus), is based on the function of intact innate immune mechanisms in the epidermis, mainly provided by keratinocytes. They establish the local cytokine and chemokine milieu which is
Margarete, Niebuhr +2 more
openaire +2 more sources
Assessment of TLR-2 concentration in tick-borne encephalitis and neuroborreliosis
Scandinavian Journal of Clinical and Laboratory Investigation, 2019The aim of the study was to check whether measurement of TLR-2 in serum or cerebrospinal fluid (CSF) can help differentiate between neuroborreliosis (NB) and tick-borne encephalitis (TBE). Eighty patients with meningitis and meningoencephalitis were divided into two groups: Group I - patients with NB (n = 40) and Group II - patients with TBE (n = 40 ...
Moniuszko-Malinowska, Anna +8 more
openaire +4 more sources
Allergy, 2008
Background: Atopic dermatitis (AD) is often complicated by an enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus. Toll‐like receptors (TLR), especially TLR‐2 recognizes cell wall components of S. aureus, e.g. lipoteichoic acid (LTA) and peptidoglycan (PGN).
M, Niebuhr +5 more
openaire +2 more sources
Background: Atopic dermatitis (AD) is often complicated by an enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus. Toll‐like receptors (TLR), especially TLR‐2 recognizes cell wall components of S. aureus, e.g. lipoteichoic acid (LTA) and peptidoglycan (PGN).
M, Niebuhr +5 more
openaire +2 more sources
Human neutrophils and TLRs: 2, 4, and plenty more
Blood, 2003And who could be truly surprised? Toll-like receptors (TLRs) are orthologs of combined developmental polarization and host defense proteins identified in the fruit fly, Drosophila melanogaster , and respond to molecular motifs that are distinct and unique features of bacterial, fungal, and ...
openaire +1 more source