Results 91 to 100 of about 17,805,524 (287)
Annals of Gastroenterological Surgery, EarlyView.MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song +6 more
wiley +1 more source
Indian Journal of Animal Sciences, 2016 This study was conducted to observe the effects of dietary noni and kalmegh supplementation on production performance, immunity and gene expression of toll-like receptors in Nicobari fowl. Supplementation of noni and kalmegh significantly influenced the
JAI SUNDER, T SUJATHA, A RAJA, A KUNDU
doaj +1 more source
Immunobiology, 2015 It has been reported that Staphylococcus aureus survives within macrophages by hijacking host cell surface Toll-like receptor-2 (TLR-2). Moreover, S. aureus infection induced activation of TLR-2 has been reported to downregulate the expression of CC-chemokine receptor-2 (CCR-2), a receptor essential for binding of chemokines to propagate phagocytosis ...
Biswadev, Bishayi +3 more
openaire +2 more sources
Relative expression of TLR-2 and TLR-4 mRNA.
, 2021 RT-qPCR data were obtained using the cDNA of non-infected (NI) and single-infected (SI) BALB/c and C57BL/6 mice and re-infected (RE) BALB/c mice (n = 5 / group). The relative expression of TLR-2 and TLR-4 mRNA was normalized to the reference gene β-actin
Fabrício Marcus Silva Oliveira (8039150) +18 more
core +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
Frontiers in ImmunologyBackgroundSince rapid and accurate diagnosis of pneumonia and determination of its severity remain challenging, particularly in childhood, we aimed to evaluate the role of toll-like receptors (TLR) in pneumonia, which has been limited in animal and adult
Ozlem Necipoglu +9 more
doaj +1 more source
Influence of TLR-2 in the immune response in the infection induced by fungusSporothrix schenckii
Immunological Investigations, 2014 Toll-like receptors (TLRs) play an important role in immunity, since they bind to pathogen surface antigens and initiate the immune response. However, little is known about the role of TLR-2 in the recognition of S. schenckii and in the subsequent immune response.
Negrini, Thais De C. +6 more
openaire +4 more sources
Hepatic and aortic mRNA expression of toll-like receptor (TLR)-2 and TLR-4.
, 2014 The baseline mRNA expressions of TLR-2 and TLR-4 were higher in the liver than in the aorta. Changes in mRNA expression in response to the cholesterol diet and/or carrageenan injection were substantially different between tissues. mRNA expressions of TLR-
Eung Ju Kim (573340) +6 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source