Results 171 to 180 of about 150,598 (283)

Identification of TLR-2-activating lipoproteins in Staphylococcus aureus

Identification of TLR-2-activating lipoproteins in Staphylococcus aureus
学位論文の要旨
openaire  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Fasudil improves neutrophilic asthma by influencing M1 macrophage polarization and the expression of the NF-κB/TLR-2/RPS3 pathway. [PDF]

Am J Transl Res
Guo SD, Liu CY, Liu R, Zhang YP, Zuo LY, Cui CY, Cheng J, Lin T.   +7 more
europepmc   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Probiotic bacteria Bifidobacterium bifidum upregulation of intestinal epithelial tight junction barrier is mediated by TLR-2/TLR-6 receptor complex activation of occludin gene. [PDF]

NPJ Biofilms Microbiomes
Abdulqadir R, Al-Sadi R, Gupta Y, Rawat M, Ma T.   +4 more
europepmc   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

Equine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

TLR 2/6/9 Agonist PUL-042 [PDF]

, 2020
openaire   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Serum TLR2 and S100B in Substance Abuse: A Clinical Perspective

International Journal of Medical Toxicology and Forensic Medicine
Background: Substance abuse leads to blood-brain barrier dysfunction and activation of neuro-inflammatory pathways. However, the contribution of serum levels of Toll-like receptor 2 (TLR-2) and S100 calcium-binding protein B (S100B) to neuropsychological
Babak Mostafazadeh, Mahtab Ramezani, Leila Simani, Shahin Shadnia, Fatemeh Abbaszadeh, Peyman Erfantalab Evini, Somayeh Monjazeb, Mitra Rahimi, Hossein Pakdaman, Faezeh Maghsudloo   +9 more
doaj  

<i>Porphyromonas gingivalis</i> Lysate Induces TLR-2/4-Dependent NF-κB Activation and Inflammatory Damage in the Human Placental Barrier. [PDF]

Int J Mol Sci
Araneda-Rojas S, Castillo C, Liempi A, Fernández-Moya A, Guerrero-Muñoz J, Alfaro S, Gallardo C, Arregui R, Hoare A, Gleisner MA, Hernández M, Kemmerling U.   +11 more
europepmc   +1 more source