<i>Lactobacillus acidophilus</i> inhibits the TNF-α-induced increase in intestinal epithelial tight junction permeability via a TLR-2 and PI3K-dependent inhibition of NF-κB activation. [PDF]
Haque M +7 more
europepmc +1 more source
Mycoplasma gallisepticum triggers immune damage in the chicken thymus by activating the TLR-2/MyD88/NF-κB signaling pathway and NLRP3 inflammasome. [PDF]
Chen C +4 more
europepmc +1 more source
Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass +2 more
wiley +1 more source
Clinicopathological Significance and Prognostic Role of High Mobility Group Box 1 (HMGB1), Toll-Like Receptor (TLR) 2 and TLR4 in Breast Cancer. [PDF]
Taguchi R +6 more
europepmc +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Abstract Wilson disease (WD) is an autosomal recessive disorder of hepatic copper metabolism with varied clinical presentations. We describe a 15‐year‐old male referred for elevated aminotransferases, burning facial pruritis, scalp dysesthesias, and chronic bilateral lower extremity edema.
Tierra L. R. Mosher +2 more
wiley +1 more source
Expression of Concern: Divergent Roles of Amino Acid Residues Inside and Outside the BB Loop Affect Human Toll-Like Receptor (TLR)2/2, TLR2/1 and TLR2/6 Responsiveness. [PDF]
PLOS ONE Editors.
europepmc +1 more source
Abstract Purpose To compare early patient‐reported clinical outcomes of patient‐individual total knee arthroplasty (TKA) with individualized trochlear design versus robotic‐assisted TKA using off‐the‐shelf implants in patients with valgus knee phenotypes and pronounced femoral valgus (lateral distal femoral angle [LDFA] < 85°) at 3 and 12 months ...
Lars‐Rene Tuecking +5 more
wiley +1 more source
Validation of a Toll-like Receptor (TLR)2/TLR1 Activation Assay for Biological Standardization of Arthrospira/Limnospira Immune-Enhancing Potency. [PDF]
Haron MH +4 more
europepmc +1 more source
Abstract Purpose Robotic‐arm‐assisted surgery is increasingly used in orthopaedics due to its potential clinical benefits. This real‐world data analysis evaluated the impact of image‐based, robotic‐arm‐assisted total knee arthroplasty (raTKA) over non‐robotic‐arm‐assisted total knee arthroplasty (nraTKA) on perioperative outcomes in Germany based on a ...
Lars‐Rene Tuecking +7 more
wiley +1 more source

