Results 251 to 260 of about 150,598 (283)

TLR‐2‐mediated cytokine and chemokine secretion in human keratinocytes

Experimental Dermatology, 2010
Abstract:  The human epidermis provides a first line of defense against exogenous pathogens. Resistance to bacterial skin infections, e.g. with Staphylococcus aureus (S. aureus), is based on the function of intact innate immune mechanisms in the epidermis, mainly provided by keratinocytes. They establish the local cytokine and chemokine milieu which is
Margarete, Niebuhr, Kathrin, Baumert, Thomas, Werfel   +2 more
openaire   +2 more sources

Assessment of TLR-2 concentration in tick-borne encephalitis and neuroborreliosis

Scandinavian Journal of Clinical and Laboratory Investigation, 2019
The aim of the study was to check whether measurement of TLR-2 in serum or cerebrospinal fluid (CSF) can help differentiate between neuroborreliosis (NB) and tick-borne encephalitis (TBE). Eighty patients with meningitis and meningoencephalitis were divided into two groups: Group I - patients with NB (n = 40) and Group II - patients with TBE (n = 40 ...
Moniuszko-Malinowska, Anna, Penza, Paweł, Pancewicz, Sławomir, Świerzbińska, Renata, Król, Monika, Zajkowska, Joanna, Czupryna, Piotr, Zajkowska, Olga, Dunaj, Justyna   +8 more
openaire   +4 more sources

Dysregulation of toll‐like receptor‐2 (TLR‐2)‐induced effects in monocytes from patients with atopic dermatitis: impact of the TLR‐2 R753Q polymorphism

Allergy, 2008
Background:  Atopic dermatitis (AD) is often complicated by an enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus. Toll‐like receptors (TLR), especially TLR‐2 recognizes cell wall components of S. aureus, e.g. lipoteichoic acid (LTA) and peptidoglycan (PGN).
M, Niebuhr, J, Langnickel, C, Draing, H, Renz, A, Kapp, T, Werfel   +5 more
openaire   +2 more sources

Human neutrophils and TLRs: 2, 4, and plenty more

Blood, 2003
And who could be truly surprised? Toll-like receptors (TLRs) are orthologs of combined developmental polarization and host defense proteins identified in the fruit fly, Drosophila melanogaster , and respond to molecular motifs that are distinct and unique features of bacterial, fungal, and ...
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TLR-2 is involved in airway epithelial cell response to air pollution particles

Toxicology and Applied Pharmacology, 2005
Primary cultures of normal human airway epithelial cells (NHBE) respond to ambient air pollution particulate matter (PM) by increased production of the cytokine IL-8, and the induction of several oxidant stress response genes. Components of ambient air PM responsible for stimulating epithelial cells have not been conclusively identified, although metal
Susanne, Becker, Lisa, Dailey, Joleen M, Soukup, Robert, Silbajoris, Robert B, Devlin   +4 more
openaire   +2 more sources

Ubiquitin-like protein MNSFβ regulates TLR-2-mediated signal transduction

Molecular and Cellular Biochemistry, 2012
Post-translational modification by monoclonal nonspecific suppressor factor β (MNSFβ) has been involved in the regulation of a variety of cellular processes. Previous studies have demonstrated that MNSFβ covalently binds to the intracellular pro-apoptotic protein Bcl-G and regulates TLR-4-mediated signal transduction. Recently, we found that MNSFβ also
Morihiko, Nakamura, Jun, Watanabe, Natsuko, Watanabe   +2 more
openaire   +2 more sources

Identification of TLR-2-activating lipoproteins in Staphylococcus aureus

2009
Doctor of Philosophy in ...
125723, Tawaratsumida, Kazuki
openaire   +1 more source

Impaired TLR-2 expression and TLR-2-mediated cytokine secretion in macrophages from patients with atopic dermatitis

Yearbook of Dermatology and Dermatologic Surgery, 2011
openaire   +1 more source

[Cloning of mouse TLR-2 gene and its expression in Pichia pastroris].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2005
To clone the mouse TLR-2 gene and to express it in Pichia pastroris.Full-length gene encoding mouse Toll-like receptor 2 (mTLR-2) was amplified by RT-PCR, cloned into pUCm-T vector, and confirmed by sequencing. The target gene was then inserted into Pichia pastroris expression vector pPICZalphaC, which was transformed into Pichia pastroris.
Wen-zhong, Zhao, Hai-yan, Jiang, Yan-jun, Liu, Ping, Zhu, Ning, Fu   +4 more
openaire   +1 more source

20-OR: Engagement of the TLR-2 in Cardiac Allograft Rejection

Human Immunology, 2010
D. Olga McDaniel, Xinchun Zhou, Zelda He, Giorgio Aru, Charles K. Moore   +4 more
openaire   +1 more source