Results 141 to 150 of about 13,006,177 (289)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Some peculiarities of premorbid background and pneumonias clinical course in patients with grippe with TLR-2, TLR-3, TLR-4 genes polymorphism

, 2013
Проаналізовано преморбідний фон і перебіг грипу, ускладненого пневмонією, у пацієнтів із поліморфізмом Arg753Gln гену TLR-2, Leu412Phe гену TLR-3, Asp299Gly гену TLR-4.
Pryimenko, N. O., Прийменко, Наталія Олегівна, Прийменко, Наталья Олеговна   +2 more
core   +1 more source

Final 2‐Year Results of the REFORM Study: A Randomized Trial of Biolimus DCB Versus Paclitaxel DCB for In‐Stent Restenosis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In the REFORM trial, treatment of coronary in‐stent restenosis with a Biolimus A9™ drug‐coated balloon (BCB) was found to be inferior with respect to in‐segment percentage stenosis at 6‐months in comparison to treatment with a standard paclitaxel coated paclitaxel‐coated balloon (PCB). Aims In this manuscript, the final prespecified
Daniel O'Callaghan, J. J. Coughlan, Fernando Alfonso, Joo‐Yong Hahn, Manel Sabate, Ralph Toelg, Samuel Copt, Sean Fitzgerald, Marie‐Claude Morice, Jasper Trevelyan, Darren Mylotte, Antonio Fernandez Ortiz, Rory Durand, Jochen Wöhrle, Franz Xever Kleber, Giuilo Stefanini, Himanshu Rai, Peter O'Kane, Robert A. Byrne   +18 more
wiley   +1 more source

Detection of Post‐Stent Medial Dissection and White Thrombus Using Hybrid IVUS OCT Imaging may Help Guide Management

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We present a 66‐year‐old undergoing ostial‐to‐mid right coronary artery (RCA) percutaneous coronary intervention (PCI) lesion proximal to an existing stent in the mid‐to‐distal segment. The patient underwent PCI, with intravascular imaging using the Novasight Hybrid IVUS OCT (Conavi, Toronto, CA) which revealed a proximal edge dissection and ...
Natali Sorajja, Khady N. Fall, Jeffrey W. Moses, Megha Prasad   +3 more
wiley   +1 more source

Тhe prevalence of TLR-2, TLR-3, TLR-4 genes polymorphism in patients with complicated grippe course and its effect estimation on grippe-associated pneumonia course

, 2013
Метою цього дослідження було вивчити поширеність та оцінити вплив поліморфізму генів Arg753Gln TLR-2, Leu412Рhe TLR-3, Asp299Gly TLR-4 на перебіг грип-асоційованої пневмонії. В групу здорових осіб увійшли 148 мешканців Полтавської області та 46 хворих на
Pryimenko, N. O., Прийменко, Наталія Олегівна, Прийменко, Наталья Олеговна   +2 more
core   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani, Gonzalo García‐Martí, Andrés Provencio‐Regidor, Irene Serrano‐García, Adrián Jerónimo‐Baza, Alejandro Travieso, Gabriela Tirado‐Conte, Fernando Macaya‐Ten, Hernán Mejía‐Rentería, Pablo Salinas, Luis Nombela‐Franco, Pilar Jiménez‐Quevedo, Nieves Gonzalo, Javier Escaned, Antonio Fernández‐Ortiz, Iván J. Núñez‐Gil   +15 more
wiley   +1 more source

Five‐Year Clinical Outcomes of Biodegradable Versus Durable Polymer Drug‐Eluting Stents: A Propensity Score‐Matched Analysis of 4394 Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee, Hong‐Seok Lim, Kyoung‐Woo Seo, Hyoung‐Mo Yang, So‐Yeon Choi, Seung‐Jea Tahk, Myeong‐Ho Yoon   +6 more
wiley   +1 more source

Intravascular Lithotripsy in Left Main Stem Percutaneous Coronary Intervention

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background IVL is increasingly used for coronary calcium modification; however, prospective data for its use in LMS lesions are lacking. Aims To evaluate the feasibility, safety, and mechanical efficacy of intravascular lithotripsy (IVL) for calcium modification in calcified distal left main stem (LMS) percutaneous coronary intervention ...
Claudia S Cosgrove, Retesh Bajaj, Ganeev Malhotra, Francis R Joshi, Akiko Maehara, Andrew McNeice, Margaret McEntegart, Gao Ong, Novalia Sidik, Julian W Strange, Simon Walsh, Ian Webb, Simon Wilson, Jiawei Wu, James C Spratt   +14 more
wiley   +1 more source

支气管肺泡灌洗液及血清NF-κB、TLR-2、TLR-4、 TNF-α在肺炎诊断中的应用价值

Zhongguo shiyan zhenduanxue
目的 探讨支气管肺泡灌洗液(BALF)及血清核转录因子-κB(NF-κB)、Toll样受体2(TLR-2)、Toll样受体4(TLR-4)、肿瘤坏死因子α(TNF-α)在肺炎诊断中的应用价值。方法 选取2023年1月—2024年3月于吉林大学第二医院就诊的57例肺炎患者纳入研究组，另取同期体检的健康者57例纳入对照组，均采集外周静脉血与肺泡灌洗液，检测NF-κB、TLR-2、TLR-4、TNF-α水平，采用Pearson相关性分析患者血清及BALF中NF-κB、TLR-2、TLR-4、TNF-α的相关性。
金美玉, 王冠, 林文婷, 吴艳峰
doaj  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source