Results 141 to 150 of about 136,665 (214)

⁠⁠Functional Foods Alleviate Behavioral Alterations and Improve GABAergic System Regulating TLR-4/NF-κB Axis in Valproic-Induced Autism. [PDF]

Brain Behav
Molinari F, Fusco R, Siracusa R, D'Amico R, Impellizzeri D, Abdelhameed AS, Fritsch T, Jacob UM, Cuzzocrea S, Calabrese V, Paola RD, Cordaro M.   +11 more
europepmc   +1 more source

Itching for a diagnosis: Dysesthesias as an atypical presentation of Wilson disease in an adolescent—Case report

JPGN Reports, EarlyView.
Abstract Wilson disease (WD) is an autosomal recessive disorder of hepatic copper metabolism with varied clinical presentations. We describe a 15‐year‐old male referred for elevated aminotransferases, burning facial pruritis, scalp dysesthesias, and chronic bilateral lower extremity edema.
Tierra L. R. Mosher, John Hicks, Krupa R. Mysore   +2 more
wiley   +1 more source

Artesunate-mycophenolate Mofetil Dimer Micelles Alleviate Allogeneic Skin Graft Rejection by Inhibiting the TLR-4 Pathway in Macrophages. [PDF]

Theranostics
Zhao W, Yang Z, Tang H, Zheng J, Liang Z, Sun R, Wang N, Su R, Wang H, Qiao Y, Zheng S, Song P, Xie H.   +12 more
europepmc   +1 more source

Superior patient‐reported clinical outcomes after patient‐individual total knee arthroplasty compared with off‐the‐shelf robotic‐assisted total knee arthroplasty in valgus knee phenotypes

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare early patient‐reported clinical outcomes of patient‐individual total knee arthroplasty (TKA) with individualized trochlear design versus robotic‐assisted TKA using off‐the‐shelf implants in patients with valgus knee phenotypes and pronounced femoral valgus (lateral distal femoral angle [LDFA] < 85°) at 3 and 12 months ...
Lars‐Rene Tuecking, Peter Savov, Mara Hold, Ricarda Stauss, Henning Windhagen, Max Ettinger   +5 more
wiley   +1 more source

Neuroprotective and anticonvulsant effect of trimetazidine in a PTZ-kindling model of mice through modulation of the IL-1β/IL-1R1 and HMGB-1/TLR-4 axis. [PDF]

Front Pharmacol
Ahmad S, Samim M, Jain S, Vohora D, Nidhi.   +4 more
europepmc   +1 more source

Reduced length of stay and improved perioperative outcomes in robotic‐arm‐assisted TKA: A real‐world evidence study of 63,931 cases from German hospitals

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic‐arm‐assisted surgery is increasingly used in orthopaedics due to its potential clinical benefits. This real‐world data analysis evaluated the impact of image‐based, robotic‐arm‐assisted total knee arthroplasty (raTKA) over non‐robotic‐arm‐assisted total knee arthroplasty (nraTKA) on perioperative outcomes in Germany based on a ...
Lars‐Rene Tuecking, Marco Ezechieli, Christoph Barkhausen, Christian Hendrich, Lea Charlotte Wienholt, Christoph Pross, Rüdiger von Eisenhart‐Rothe, Henning Windhagen   +7 more
wiley   +1 more source

Toll-like receptor 4 (TLR-4) polymorphisms and asthma risk in rural and urban settings: findings from the UK biobank. [PDF]

Ups J Med Sci
Kisiel MA, Rask-Andersen M, Johansson Å, Ek WE, Rask-Andersen A.   +4 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Assessment of dermal sensitization by nickel salts in a novel humanized TLR-4 mouse model. [PDF]

J Immunotoxicol
Roach KA, Anderson SE, Waggy C, Aldinger J, Stefaniak AB, Roberts JR.   +5 more
europepmc   +1 more source

The Airway Epithelial Barrier in Childhood Asthma: A Central Player in Glucocorticoid Therapy, Resistance, and Severe Asthma

Pediatric Discovery, EarlyView.
ABSTRACT Childhood asthma remains a global public health challenge with suboptimal control, despite the availability of inhaled corticosteroids (ICS) as first‐line therapy. Glucocorticoids suppress inflammation and protect the airway epithelial barrier (AEB) via genomic and nongenomic pathways.
Tangqiaochu Gan, Zhou Fu, Chao Niu
wiley   +1 more source