Results 241 to 250 of about 13,006,177 (289)

Anti-inflammatory effects of Mentha pulegium L. extract on human peripheral blood mononuclear cells are mediated by TLR-4 and NF-κB suppression. [PDF]

Heliyon
Mohammadi F, Rahimi K, Ahmadi A, Hooshmandi Z, Amini S, Mohammadi A.   +5 more
europepmc   +1 more source

Fermented Protaetia brevitarsis Larvae Ameliorates Chronic Ethanol-Induced Hepatotoxicity in Mice via AMPK and TLR-4/TGF-β1 Pathways. [PDF]

J Microbiol Biotechnol
Lee HL, Kim JM, Go MJ, Joo SG, Kim TY, Lee HS, Kim JH, Son JS, Heo HJ.   +8 more
europepmc   +1 more source

TLR-4 polymorphisms and leukocyte TLR-4 expression in febrile UTI and renal scarring

Pediatric Nephrology, 2013
In this study, we aimed to determine the relation of TLR-4 Asp299Gly and Thr399Ile polymorphisms and monocyte/neutrophil TLR-4 expression to febrile urinary tract infection (UTI) and renal scar development in ...
Sefa Kızıldağ, Halil Ates, Alper Soylu   +2 more
exaly   +5 more sources

TLR Polymorphisms in FMF: Association of TLR-2 (Arg753Gln) and TLR-4 (Asp299Gly, Thre399Ile) Polymorphisms and Myeloid Cell TLR-2 and TLR-4 Expression with the Development of Secondary Amyloidosis in FMF

Inflammation, 2010
Amyloidosis is the major complication of familial Mediterranean fever (FMF). Toll-like receptors (TLR) are involved in the activation of an innate immune system TLR-2 and TLR-4 recognize lipoteichoic acid and lipopolysaccharides (LPS), respectively ...
Halil Ates, Belde Kasap-Demir
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

TLR‐4 targeting contributes to the recovery of osteoimmunology in periodontitis

Journal of Periodontal Research, 2021
AbstractObjectiveThe aim of this study was to determine the potential role of TLR‐4 in the osteoimmunological imbalance of periodontitis.BackgroundAlthough current evidence supports that TLR‐4 plays an important role in the inflammatory response of periodontal tissues triggered by microorganisms, little information is available regarding the function ...
Xi Yang, Xiaoan Tao, Weijuan Qi, Zhao Liu, Yamin Wang, Qianqian Han, Chenrong Xu   +6 more
openaire   +2 more sources

Hemorrhage-induced acute lung injury is TLR-4 dependent

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2004
Toll-like receptor 4 (TLR-4), initially identified as an LPS receptor, is critical to the signaling of a variety of danger signals, including heat shock protein 60, fibrinogen, and fibronectin. Recent data also suggest that TLR-4 plays a role in determining survival in both endotoxemia and hemorrhagic shock.
Katherine A, Barsness, John, Arcaroli, Alden H, Harken, Edward, Abraham, Anirban, Banerjee, Leonid, Reznikov, Robert C, McIntyre   +6 more
openaire   +2 more sources

Cloning, expression and bioinformatics analysis of the duck TLR 4 gene

British Poultry Science, 2012
1. Toll-like receptors (TLRs) are type I transmembrane proteins that play an essential role in the innate immune system. Studies on the structure and function of TLRs can be applied to the development of new approaches to control diseases of humans and animals. 2. A 3432-bp cDNA encoding duck toll-like receptor 4 (duTLR4) was cloned from duck splenic
H, Jia, G, Li, J, Li, Y, Tian, D, Wang, J, Shen, Z, Tao, J, Xu, L, Lu   +8 more
openaire   +2 more sources

Hyaluronan differently modulates TLR‐4 and the inflammatory response in mouse chondrocytes

BioFactors, 2012
AbstractHyaluronic acid (HA) may exert different action depending on its degree of polymerization. Small HA fragments induce proinflammatory responses, while highly polymerized HA exerts a protective effect in inflammatory pathologies such as rheumatoid arthritis.
CAMPO, Giuseppe Maurizio, AVENOSO, Angela, D'ASCOLA, ANGELA, Prestipino V, Scuruchi M, Nastasi G, CALATRONI, Alberto, CAMPO, Salvatore Giuseppe   +7 more
openaire   +3 more sources

TLR-4: a promising target for chemotherapy-induced peripheral neuropathy

Molecular Biology Reports
Chemotherapy-induced peripheral neuropathy (CIPN) affects a significant majority of cancer patients, with up to 80% experiencing this severe and dose-limiting side effect while undergoing anti-cancer treatment. CIPN can be induced by a variety of drugs commonly employed in the management of both solid tumors and hematologic cancers. The inadequacies in
Nagendra, Babu, Anagha, Gadepalli, , Akhilesh, Dilip, Sharma, Anurag Kumar, Singh, Deepak, Chouhan, Somesh, Agrawal, Vinod, Tiwari   +7 more
openaire   +2 more sources

HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2

Shock, 2006
In response to bacterial endotoxin (e.g., LPS) or endogenous proinflammatory cytokines (e.g., TNF and IL-1beta), innate immune cells release HMGB1, a late cytokine mediator of lethal endotoxemia and sepsis. The delayed kinetics of HMGB1 release makes it an attractive therapeutic target with a wider window of opportunity for the treatment of lethal ...
Man, Yu, Haichao, Wang, Aihao, Ding, Douglas T, Golenbock, Eicke, Latz, Christopher J, Czura, Matthew J, Fenton, Kevin J, Tracey, Huan, Yang   +8 more
openaire   +2 more sources