Divergent cis-regulatory haplotypes at Tlr2 are associated with immune responsiveness. [PDF]
Nandakumar M +5 more
europepmc +1 more source
Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights
Summary of the microbiome‐lipid‐microinflammation axis in androgenetic alopecia (AGA). Altered sebaceous gland activity, shifts in microbial abundance on the scalp and hair follicle, and follicular microinflammation interact bidirectionally, each reinforcing the others.
Aditya K. Gupta +3 more
wiley +1 more source
In Silico Identification of Dual-Action Compounds Targeting TLR2 and <i>Streptococcus mutans</i> Proteins for the Prevention of Early Childhood Caries. [PDF]
Guzmán-Flores JM +7 more
europepmc +1 more source
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen +1 more
wiley +1 more source
APOE4-Expressing Astrocytes Exhibit Parkinson's Disease-Related Pathology. [PDF]
Nechushtai L +5 more
europepmc +1 more source
ABSTRACT Tea polyphenols (TPs) are natural bioactive compounds extensively used in aquaculture diets as a functional supplement because of their antioxidant, antimicrobial and immunomodulatory potential. Four isonitrogenous diets (crude protein: 30%) were designed with incorporating TPs at levels of 0% (control, TPs‐0), 0.025% (TPs‐1), 0.05% (TPs‐2 ...
Shishir K. Nandi +4 more
wiley +1 more source
TLR2 Activation Enhances Inflammatory Signaling and Accelerates Cyst Growth and Renal Fibrosis in Polycystic Kidney Disease Mice. [PDF]
Wei A +10 more
europepmc +1 more source
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Toll-like receptors: versatile players in tumor. [PDF]
Yang Y, Pi R.
europepmc +1 more source
The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management
(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi +8 more
wiley +1 more source

