Results 171 to 180 of about 103,839 (247)

Identification and Experimental Validation of Biomarkers Associated with PI3K/AKT Signaling Pathway in Spinal Cord Injury. [PDF]

Mol Neurobiol
Chen T, Yu L, Cai Z, Chen L.
europepmc   +1 more source

The Toll‐Like Receptor Signalling Pathway Is Altered in iPSC‐Derived Cortical Networks From People With Bipolar Disorder

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Induced pluripotent stem cell (iPSC)‐derived brain cells are widely utilised as in vitro models for several neuropsychiatric disorders, as they retain the donor's genetic profile, offering a unique opportunity to study living human brain cells and perform controlled experimental manipulations.
Bruna Panizzutti, Chiara Cristina Bortolasci, Megan Ellis, Briana Spolding, Courtney Swinton, Trang T. T. Truong, Cassie Field, Zoe Shih‐Jung Liu, Damián Hernández, Greg Roebuck, Ajeet B. Singh, Bruno Agustini, Robson Zazula, Ana C. Andreazza, Dana El Soufi El Sabbagh, Hyunjin Jeong, Olivia M. Dean, Jee Hyun Kim, Michael Berk, Ken Walder   +19 more
wiley   +1 more source

System immunoinformatics-based design of a multi-epitope vaccine candidate against La Crosse virus. [PDF]

PLoS One
Masum MHU, Heema HP, Mahdeen AA, Lokman SM, Tasnim Z, Hasan MR, Arpa SH, Parvin R, Ferdous J, Uddin MS.   +9 more
europepmc   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

British Journal of Pharmacology, Volume 183, Issue 16, Page 4592-4609, August 2026.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu, Zengbing Lu, Julia Yuen Hang Liu, Man Piu Ngan, Kai‐Hei Tse, John Anthony Rudd   +5 more
wiley   +1 more source

Linking inflammation, metabolic dysfunction, and neurodegeneration: a comprehensive review of TLR2 pathways in type 2 diabetes. [PDF]

Front Clin Diabetes Healthc
Arreguín-Cano JA, Santana-Delgado SA, Villegas-Mercado CE, Orozco-Molina GG, González-Acosta A, Bermúdez M.   +5 more
europepmc   +1 more source

Efficacy of 1064 nm Fractional Q‐Switched Laser and Topical Isotretinoin: A Split‐Face Randomized Clinical Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Introduction Acne scars are a common complaint amongst dermatology patients and treating these scars effectively can still be challenging. Multiple treatment approaches can be used on this matter, one of which is using various types of lasers. On the other hand, one of the most effective medical treatments for acne is topical retinoids, which ...
Gita Faghihi, Maryam Aghaei, Hamid Varastehpour, Sarah Seyedyousefi, Bahareh Abtahi‐Naeini   +4 more
wiley   +1 more source

Combating Streptococcus agalactiae infections by designing a multi-epitope vaccine using molecular dynamic simulations. [PDF]

J Genet Eng Biotechnol
Arya J, Kaushik D, Berwal B, Kumar A, Kumar R, Budhwar S, Chaudhary N, Dahiya H, Nain K, Chhillar A, Dangi M.   +10 more
europepmc   +1 more source

Impact of Oral Herbal Supplementation on Human Skin Aging: A Systematic Review of Clinical Trials

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Background Skin aging, characterized by wrinkles, decreased elasticity, and dryness, is both a public health and esthetic issue, affecting most adults and leading to lowered quality of life and higher healthcare costs. While topical treatments are common, systemic approaches are gaining interest for their potential to enhance skin hydration ...
Gisela Meydilin Sanjaya, Brilian Veda Kartika Putri, Hany Anneke, Nayla Majeda Alfarafisa, Astrid Feinisa Khairani, Nur Atik   +5 more
wiley   +1 more source

Myeloid TLR2 signaling amplifies immunopathology in influenza-infected murine neonates. [PDF]

Am J Respir Cell Mol Biol
Rao AS, Onufer AP, Kumova O, Roberts LTN, Mossabeb R, Pascasio J, Carey AJ.   +6 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source