Results 241 to 250 of about 133,056 (344)

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

American Journal of Hematology, Volume 100, Issue 8, Page 1323-1333, August 2025.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu, Sofiya Tsyplenkova, Carine Fillebeen, Kostas Pantopoulos   +3 more
wiley   +1 more source

TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system. [PDF]

Commun Biol
Mansouri A, Akthar I, Miyamoto A.
europepmc   +1 more source

TLR2 modulates inflammation in zymosan-induced arthritis in mice. [PDF]

, 2005
Matthias Frasnelli, David Tarussio, Véronique Chobaz-Péclat, Nathalie Busso, Alexander So   +4 more
openalex   +1 more source

Role of CD44 in Regulating TLR2 Activation of Human Macrophages and Downstream Expression of Proinflammatory Cytokines

Journal of Immunology, 2018
Marwa M. Qadri, S. Almadani, G. Jay, Khaled A. Elsaid   +3 more
semanticscholar   +1 more source

The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
LncRNAs are localized in cytosol, nucleus, other sub‐nuclear compartments, and exosomes in the cell, and play significant role in lung cancer dissemination based on their localizations. LncRNAs have emerged as promising biomarkers for both early detection and prognosis.
Musaffe Tuna, Gordon B Mills, Christopher I. Amos   +2 more
wiley   +1 more source

Bevacizumab cured age-related macular degeneration (AMD) via down-regulate TLR2 pathway

Open Life Sciences, 2014
Wang Zhi, Qiao Bao, Li Guo, Li Shi, Wang Li, Dong Ying   +5 more
doaj   +1 more source

Lipoprotein <i>N</i>-terminal modification in <i>Bacillus</i>: a new paradigm for extracellular acetylation and species-dependent Toll-like receptor 2 immunomodulation. [PDF]

mBio
Komazin G, Wigmore RM, Ranade AM, Rizk AA, Gardiner JH, Meredith TC.   +5 more
europepmc   +1 more source

The Mucosal Adjuvant Macrophage-Activating Lipopeptide-2 Directly Stimulates B Lymphocytes via the TLR2 without the Need of Accessory Cells [PDF]

, 2005
Stefan Borsutzky, Karsten Kretschmer, Pablo D. Becker, Peter F. Mühlradt, Carsten J. Kirschning, Siegfried Weiß, Carlos A. Guzmán   +6 more
openalex   +1 more source

Intensive Value Utilization of Food‐Derived Marine Immunoactive Peptides: Optimizing the Process Yield and Improving the Delivery Efficiency According to the Immune Activity Mechanism and Assisted Enzymatic Hydrolysis

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
To investigate the impact of assisted enzymatic hydrolysis on enhancing protein yield and biological activity. The analysis of the potential mechanism of intestinal immune regulation mediated by intestinal microorganisms is conducted. This article provides a review of the potential uses of functional, immunoactive peptides in food delivery and offers ...
Zhicheng Yin, Yingying Tian, Shuteng Huang, Hong Wang, Lili Zhao, Ruyue Zhang, Desheng Cai, Shuping Wang, Shaojing Zhong, Jiayu Zhang   +9 more
wiley   +1 more source

Toll like receptor 2 mediated exacerbation of sepsis associated acute kidney injury by renal congestion in mice. [PDF]

Sci Rep
Nakamura I, Umehara M, Yagi-Tomita A, Yamamoto S, Sawai S, Nakamura M, Minamida A, Yamauchi-Sawada H, Sunahara Y, Matoba Y, Okuno-Ozeki N, Nakai K, Nakata T, Kitani T, Yamashita N, Komaki K, Kirita Y, Tamagaki K, Matoba S, Kusaba T.   +19 more
europepmc   +1 more source