Results 241 to 250 of about 156,491 (330)

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai   +5 more
wiley   +1 more source

Exploring Emerging Therapeutic Targets in Osteosarcoma by Revisiting the Immune and Cancer-Intrinsic Hallmarks of Cancer. [PDF]

open access: yesCancers (Basel)
Tarone L   +7 more
europepmc   +1 more source

The generation of trained neutrophils in response to live cells of C. albicans is dependent on both TLR2 and Dectin-1 signalling in HSPCs.

open access: green
María Sobén (21355049)   +4 more
openalex   +1 more source

Toll-like receptor 2 (TLR2) [PDF]

open access: yesScience-Business eXchange, 2010
openaire   +1 more source

Effects of Defined Pig Microbiota on Acute Salmonellosis in Gnotobiotic Piglets

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Germ‐free piglets lack protective microbiota and are highly vulnerable to Salmonella Typhimurium LT2 infection. Pre‐colonization with defined pig microbiota supports early immune response and intestinal barrier maturation. By measuring pathogen spread, intestinal structure, goblet cell density, cytokines, and tight‐junction markers with molecular and ...
Igor Splichal   +8 more
wiley   +1 more source

Contribution of TLR2 to the Initiation of Ganglioside-triggered Inflammatory Signaling

open access: hybrid, 2008
Hee Jung Yoon   +5 more
openalex   +1 more source

Acrolein Promotes Retinal Inflammation Through Macrophage Chemotaxis by Inducing CCL2 Production From Müller Cells

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Patients with proliferative diabetic retinopathy show elevated vitreous levels of the acrolein adduct FDP‐lys and CCL2. In rat Müller glial cells (TR‐MUL5), acrolein increases Ccl2 gene expression and CCL2 secretion and promotes macrophage migration.
Kanae Fukutsu   +4 more
wiley   +1 more source

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