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Fungal Recognition by TLR2 and Dectin-1

2008
The innate immune system utilizes multiple receptors to recognize fungal pathogens, and the net inflammatory response is controlled by interactions between these receptors. Many fungi are recognized, at least in part, by Toll-like receptor 2 (TLR2) and Dectin-1.
Helen S, Goodridge, David M, Underhill
openaire   +2 more sources

Current Perspectives of TLR2 Signalling in the Retina

Toll-like receptor 2 (TLR2) signalling is crucial in initiating the innate immune response. Under normal conditions, TLR2 can recognise and respond to danger signals in the body and protect against damaging pathogens and molecules. However, dysregulation of this tightly controlled cascade has been implicated in various retinal disorders. There are many
Rachel, Dalton, Sarah, Doyle
openaire   +2 more sources

??????????????? ?????????????????????????? ?????????? TLR2 ???? TLR4 ???? ???????????????????? ???? ?????????????? ???????????????????????????? ????????????????

2014
???????????????????? ?????????????????????? ???????????????????????????????? ?????????????????????? ?????????????????? Arg753Gln ???????? TLR2 ???? Asp299Gly, Thr399Ile ???????? TLR4 ?????????? ????????, ???? ???????????????????? ?? ?????????????????????? ??????????????, ?? ?????????? ??????????????? ?????????????????????????? ???? ?????????????????? ??
openaire   +1 more source

The novel small-molecule antagonist MMG-11 preferentially inhibits TLR2/1 signaling

Biochemical Pharmacology, 2020
GÜNTHER Weindl   +2 more
exaly  

Toll-like receptor 2 heterodimers, TLR2/6 and TLR2/1 induce prostaglandin E production by osteoblasts, osteoclast formation and inflammatory periodontitis

Biochemical and Biophysical Research Communications, 2012
Tsukasa Tominari   +2 more
exaly  

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