Results 241 to 250 of about 152,328 (305)

Chemical Profiling and Biological Activity of Copaiba Oil‐Resin Samples and Development of HPLC‐DAD Method for the Analysis of β‐Caryophyllene

Biomedical Chromatography, Volume 40, Issue 5, May 2026.
ABSTRACT The Copaifera species are traditionally used for their anti‐inflammatory, antiseptic and healing properties. The objective of this study was to compare the chromatographic profiles of seven samples of copaiba oil‐resin with respect to chromatographic and physicochemical properties and to evaluate their biological activities.
Gabriel de A. P. Graça, Cláudia G. Silva, Denise de O. Scoaris, Juliana Rodrigues de Vasconcelos, André Santos Alkimim, Vanessa C. F. Mosqueira, Luciana S. Salomon, Pietra Piotto Marcellini, Isabelle Renata Martins da Silva, Janete S. C. Santos, Andreia Fonseca Silva, Carolina P. S. Moreira, Júlio C. D. Lopes, Vera L. de Almeida   +13 more
wiley   +1 more source

Protective effect of Zymosan-A against radiation-induced premature ovarian insufficiency in a murine model. [PDF]

iScience
Yu Y, Du J, Li B, Cheng Y, Lin F, Zhou J, Song Y, Liu C, Cai S.   +8 more
europepmc   +1 more source

Activation of the NF‐ĸB Signaling Pathway by Lactobacillus plantarum and Lactobacillus casei Through Modulation of TLR4 and DC‐SIGN Genes in an Oral Squamous Cell Carcinoma Rat Model

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The composition of the oral and intestinal microbiota is believed to contribute to the development of oral cancer (OC). The chronic activation of pattern recognition receptors (PRRs) has been linked to the aggressive nature and poor prognosis of various cancers.
Vahideh Faghanizadeh, Malihe Naderi, Nazila Arbab Soleimani, Ayyoob Khosravi, Mohammad Mahdi Forghanifard   +4 more
wiley   +1 more source

Computational Design of an mRNA Vaccine Targeting LRP6 for Triple‐Negative Breast Cancer Therapy

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Triple‐negative breast cancer (TNBC) presents a poorer prognosis than other breast cancer subtypes, attributed to its aggressive nature and the lack of specific therapeutic interventions. TNBC has high recurrence rates and limited survival despite current therapies, emphasizing the critical need for improved treatment options.
Pooriya Teimoori, Mohammadreza Heidari
wiley   +1 more source

Ultrasonic repression of TRPA1-dependent astrocyte reactivity confers neuroprotection in models of Lewy body dementia. [PDF]

Transl Neurodegener
Kim JH, Lee K, Koo M, Kim D, Hong JK, Choi JY, Ko HS, Shin JH, Park JM, Park J, Lee Y.   +10 more
europepmc   +1 more source

Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Ubc9 expression is downregulated in hepatocytes during hepatic I/R injury. Higher UBC9 expression is associated with improved post‐LT liver function. Ubc9 ameliorates liver damage and inflammation responses in hepatic I/R injury. Ubc9‐mediated Ninj1 SUMOylation at K103 is essential for regulating the subcellular distribution of Ninj1. Ubc9 inhibits the
Kang Huang, Li Xu, Shufang Na, Yan Xu, Qiaoyun Liu, Shaojun Ye, Cong‐Yi Wang, Wei Zhou, Qifa Ye   +8 more
wiley   +1 more source

<i><b>Muribaculum intestinale</b></i> <b>negatively impacts glioma growth in mice through the toll-like receptor 2</b>. [PDF]

Gut Microbes
Marrocco F, Cocozza G, Antonangeli F, Khan R, Pietropaolo G, Elkihel A, Favaretto G, Lin X, Mancinelli R, Busdraghi LM, Reccagni A, Scarno G, Sciumè G, Laffranchi M, Peng L, Iebba V, Sozzani S, D'Alessandro G, Limatola C.   +18 more
europepmc   +1 more source

Tumour‐derived SAA1 reprogrammes macrophages to promote CXCL1‐mediated metastasis in Ovarian Cancer

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
A distinct SAA1‐enriched tumour cell subset with metastasis‐associated features is identified in ovarian cancer. Tumour‐derived SAA1 reprograms TAM through FPR2‐mediated JAK2–STAT3 signalling to induce an immunosuppressive phenotype. The SAA1–TAM–CXCL1 axis facilitates metastatic progression in ovarian cancer. Abstract Patients with advanced high‐grade
Xuan Zhou, Huangyang Meng, Qianjing Chang, Jingjing Ren, Meichen Wen, Lin Zhang, Wenjun Cheng   +6 more
wiley   +1 more source

In Silico Design and Evaluation of TcGAPDH as a Vaccine Against Chagas Disease: A Reverse Vaccinology Approach. [PDF]

Acta Parasitol
Nava-Cuamatzi V, Buendia-Corona RE, González-Vázquez MC, Cedillo-Ramirez ML, Carabarin-Lima A.   +4 more
europepmc   +1 more source