Results 141 to 150 of about 45,202 (234)

Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice.

PLoS ONE, 2018
Chlamydia trachomatis urogenital serovars primarily replicate in epithelial cells lining the reproductive tract. Epithelial cells recognize Chlamydia through cell surface and cytosolic receptors, and/or endosomal innate receptors such as Toll-like ...
Sebastian E Carrasco, Sishun Hu, Denise M Imai, Ramesh Kumar, George E Sandusky, X Frank Yang, Wilbert A Derbigny   +6 more
doaj   +1 more source

Genomic Insights Into the Use of Green Tea (Camellia sinensis) as a Functional Feed Additive in Sustainable Aquaculture

Aquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.
ABSTRACT Aquaculture is the fastest‐growing sector of animal food production, yet it faces increasing challenges in maintaining fish health and sustainability due to the widespread use of antibiotics and synthetic feed additives. Green tea (Camellia sinensis), a natural source of polyphenols and bioactive compounds, has gained attention as a functional
Nahida Akter, Chiara Bordin, Mahima Ranjan Acharjee, S. M. Sertaz Islam, Md. Masum Reza, Mahedi Hasan, Arman Hossain, Azeez Olalekan Baki, Md. Abdullah Al Mamun Hridoy   +8 more
wiley   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

Research Landscape and Emerging Trends in Herbal Medicine for Pediatric Respiratory Tract Infections: A CiteSpace‐Based Bibliometric Analysis

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Respiratory tract infections (RTIs) are a common concern in pediatric healthcare. Although extensive literature exists on the use of herbal medicine for pediatric RTIs, no bibliometric analysis has been conducted to date. This study aims to employ bibliometric methods to evaluate the current research landscape in this field
Chencan Chi, Jianzhong Dang, Fang Zheng
wiley   +1 more source

Protective Role of Vitamins C, D, and K in the Management of Dengue: A Narrative Review to Combat the Dengue Outbreak

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Dengue fever is mostly found in tropical and subtropical regions and is spread by mosquitoes. Still now, no specific antiviral medication is available against the disease. However, several vitamins have been identified as potential dengue therapy supplements. Therefore, this study aimed to comprehensively gather data on the
Shah Md Muztahid Hasan Chowdhury, Md. Shafiul Hossen, Mohammad A. Rashid, Mahammed Shafin Ul Islam, Arafat Miah, Mohammed Safiqul Islam, Md. Abdul Barek   +6 more
wiley   +1 more source

Immunoexpression pattern of TLR3 and TLR7 in minor salivary gland adenoid cystic carcinoma and its role in prognosis

Cancer Treatment and Research Communications
Objectives: Adenoid cystic carcinoma (ACC) of the salivary glands has poor long-term prognosis and a high metastatic rate. Toll-like receptors (TLRs), first-line immune activators, have been associated with both tumor progression and suppression.
Aleksi Rytkönen, Mine Eray, Auli Suominen, Antti Mäkitie, Caj Haglund, Jaana Hagström, Hanna K. Laine   +6 more
doaj   +1 more source

Multi‐Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu, Junsen She, Xinyuan Li, Yishang Yan, Jiaying Mo, Jianzhong Sheng, Hongbo Yang, Hefeng Huang   +7 more
wiley   +1 more source

Construction of Reverse Genetics System for Feline Calicivirus FCV‐BJ616 and Proteomic Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Chunmei Xu, Jingjie Zhao, Hao Liu, Haotian Gu, Xinming Tang, Lin Liang, Jiabo Ding, Shaohua Hou, Xiaomin Zhao, Ruiying Liang   +9 more
wiley   +1 more source

TLR3 rs3775291 C/T polymorphism is associated with elevated IFN-α level in asymptomatic HTLV-1 infection

Frontiers in Cellular and Infection Microbiology
IntroductionAlterations in the immune response may influence the development of HTLV-1-associated diseases. TLR3 detects viral nucleic acids, including HTLV-1, and triggers the production of IFN-I and other cytokines. Genetic variations in TLR3 may alter
Fabiane dos Santos Ferreira, Fabiane dos Santos Ferreira, Wandrey Roberto dos Santos Brito, Wandrey Roberto dos Santos Brito, Emmanuelle Giuliana Mendes Santana, Aline Kelly Alves Oliveira, Aline Cecy Rocha de Lima, Aline Cecy Rocha de Lima, Ednelza da Silva Graça Amoras, Carlos Araujo da Costa, Maísa Silva Souza, Sandra Souza Lima, Ricardo Ishak, Izaura Maria Vieira Cayres-Vallinoto, Izaura Maria Vieira Cayres-Vallinoto, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto, Maria Alice Freitas Queiroz, Maria Alice Freitas Queiroz   +18 more
doaj   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source