Results 201 to 210 of about 170,484 (302)

Simvastatin attenuates the lipopolysaccharideinduced inflammatory response of rat pulmonary microvascular endothelial cells by downregulating toll-like receptor 4 expression

Open Medicine, 2014
Li Yi, Ding Jian-yong, Ge Biao-xue, Miao Chang-hong   +3 more
doaj   +1 more source

Probiotic supplementation increases fecal TLR4 agonists without improving disease activity in juvenile idiopathic arthritis: a randomized placebo-controlled trial. [PDF]

Gut Microbes
Durand C, Eveillard LA, Labouret M, Aeschlimann F, Belot A, Brochard K, Chassaing B, Boizeau P, Boulkedid R, Carbasse A, Cherqaoui B, Dumaine C, Dumay A, Frachette C, Hentgen V, Kedzia C, Kolta T, Koné-Paut I, Lamy-Besnier Q, Guilmin-Crepon S, Lima-Antoine L, Pillet P, Quartier P, Tellier S, Tourneur-Marsille J, Reumaux H, Vinit C, Viennois E, Meinzer U.   +28 more
europepmc   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Targeting S100A8/A9: a molecular gateway to oral inflammation, microglial activation and neuroinflammation. [PDF]

Front Immunol
Malik JA, Qamar T, Qadri AH, Faheem I.
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Engineered hollow Prussian blue nanoparticles for synergistic anti-inflammatory therapy in sepsis. [PDF]

Mater Today Bio
Song Y, Yu X, Wu M, Liu J, Wen Z, Dong D, Ye F, Zhang S.   +7 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

HIF-1α inhibits the TLR4/NF-κB signaling pathway and modulates intestinal flora in diarrhea-predominant irritable bowel syndrome. [PDF]

PLoS One
He X, Wang D, Yang B, Yan H, Ma H, Li H, Wang J, Gao Q, Yu S, Hou X, Guo S, Liao G, Duan X, Tang J.   +13 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

<i>Polygonati Odorati Rhizoma</i> Extract Ameliorates Obesity and Insulin Resistance Potentially Through Modulation of the TLR4/NLRP3 Signaling Pathway. [PDF]

Diabetes Metab Syndr Obes
Deng X, Wu Y, Chen X, Zeng J, Li W, Wang X, Luo H, Luo Y.   +7 more
europepmc   +1 more source