Results 221 to 230 of about 272,563 (343)

Efficacy and potential pharmacological mechanisms of total glucosides of paeony in treating ankylosing spondylitis in Asian populations: a meta-analysis, network pharmacology, and molecular dynamics simulation. [PDF]

Front Nutr
Mu W, Ma J, Zhang X, Su J, Wang X, Huang C.   +5 more
europepmc   +1 more source

Tlr4 Sinyal Yolağının Modellenmesi

, 2012
A principal challenge for the life sciences is to understand the organization and dynamics of those components that make up a living system. Understanding the systems of cellular processes is very similar to solving many body problems including complex interactions, in this case among a large number of genes, proteins and other molecules.
openaire   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Simvastatin attenuates the lipopolysaccharideinduced inflammatory response of rat pulmonary microvascular endothelial cells by downregulating toll-like receptor 4 expression

Open Medicine, 2014
Li Yi, Ding Jian-yong, Ge Biao-xue, Miao Chang-hong   +3 more
doaj   +1 more source

Intestinal epithelial TLR4 knock out induces sex-specific effects on gut barrier and microbiome in an activity-based anorexia model. [PDF]

Gut Microbes
Salaün C, Huré M, Guérin C, Bôle-Feysot C, Valentin A, Léon F, Lenoir S, do-Rego JL, do-Rego JC, Langlois L, Ribet D, Achamrah N, Coëffier M.   +12 more
europepmc   +1 more source

TLR4 in Atherogenesis

Journal of the American College of Cardiology, 2018
openaire   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Fire Needling Acupuncture Reduces Neutrophil Extracellular Traps (NETs) Formation and Inhibits TLR4/NF-κB/LCN2 Pathway in Psoriasis-Like Skin Lesions. [PDF]

J Inflamm Res
Wang Q, Wei J, Wang X, Yuan F, Sun J.
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Bifunctional glycolipids targeting TLR4·MD-2 and short pentraxins. [PDF]

RSC Chem Biol
Zucchetta D, Nuschy L, Gumpelmair S, Steinberger P, Wilson I, Heine H, Zamyatina A.   +6 more
europepmc   +1 more source