Compound Augmentation of Myocardial Injury in a Rat Model of Coronary Heart Disease Induced by Ischemia/Reperfusion, Rheumatoid Arthritis, and High-Fat Diet: A Molecular Mechanistic Study. [PDF]
Xu Q +5 more
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Progression of diabetic nephropathy and adverse renal outcomes: possible involvement of Toll-like receptor 4 expression. [PDF]
Saito A +10 more
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A bioinformatics pipeline for the design of a SART3-targeted cancer vaccine with enhanced immunogenicity. [PDF]
Bayat Z +3 more
europepmc +1 more source
Zearalenone causes female reproductive lipotoxicity through the ERα-CD36/TLR4 signaling pathway. [PDF]
Dai C +9 more
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Computational design of a multi-epitope vaccine against Helicobacter pylori targeting CagA, FliD, urease, and OipA with cholera toxin B subunit (CTB) adjuvant. [PDF]
Baniasadi Nejad N +4 more
europepmc +1 more source
Comment on "Dietary dimethylglycine alleviates cyclic heat stress-induced jejunal injury in yellow-feathered broilers by inhibiting the TLR4/NF-κB signaling pathway and restoring MUC2 expression". [PDF]
Sati DM, Shinde VD, Agarwal C.
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TLR4 polymorphisms and disease susceptibility
Inflammation Research, 2012Toll-like receptors (TLRs) play a central role in the regulation of the host immune system. Each TLR recognizes specific pathogen-associated molecular patterns (PAMPs). TLR4 is one of the well characterized pathogen recognition receptors (PRRs) that recognizes the lipopolysaccharide (LPS) of Gram-negative bacteria, some conserved structures from fungal
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TLR4 agonists as immunomodulatory agents
Journal of Endotoxin Research, 2006Monophosphoryl lipid A (MPL ® ) is a potent vaccine adjuvant derived from Salmonella minnesota that was recently licensed in Europe as a component of an improved vaccine for hepatitis B (Fendrix ® ). MPL, like lipopolysaccharide from which it is derived,
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Involvement of ILR4α and TLR4 in miscarriages
Journal of Reproductive Immunology, 2019The purpose of this study was to analyze the involvement of signaling via Interleukin-4-Receptor α (IL4Rα) and Toll like receptor (TLR) 4 at the fetomaternal interface in the process of early pregnancy.Placenta specimens of 46 patients in early pregnancy were analyzed (normal pregnancy (n = 15), spontaneous (n = 15) and habitual abortion (n = 16 ...
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