Results 241 to 250 of about 170,484 (302)

Engineered microvesicle-mediated multimodal therapy resolves ulcerative colitis via synergistic immunoregulation, barrier restoration, and microbiota remodeling. [PDF]

Mater Today Bio
Qi C, Liang C, Wang S, Zhang H, Wei H, He X, Chen W.   +6 more
europepmc   +1 more source

Gut Microbiota Modulation and Functional Effects of Edible and Medicinal Fungi: Sanghuangporus vaninii as a Case Study

Gut Medicine, EarlyView.
ABSTRACT Edible and medicinal fungi exert diverse biological effects, including immunomodulatory, antitumour, and anti‐inflammatory activities, as well as the amelioration of metabolic disorders. The relationship between these effects and the gut microbiota is attracting increasing attention.
Meng Teng, Wenqi Li, Di Wang, Lanzhou Li
wiley   +1 more source

Sex-Specific Anti-Inflammatory Effects of Alternate Day Fasting via TLR4 and Leptin Signaling in Middle-Aged Rats. [PDF]

J Biochem Mol Toxicol
Kilic-Erkek O, Gundogdu G, Coguplugil A, Dodurga Y.   +3 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

CIRP Promotes Redox-Inflammatory Endothelial Injury in High-Fat Diet-Fed ApoE^-/- Mice and HUVECs: Involvement of TLR4/SIRT6 Signaling. [PDF]

Antioxidants (Basel)
Chen D, Yang J, Ren L, Zheng Z, Jin Z, Gu J, Zheng N, Wang W, He J, Lin R.   +9 more
europepmc   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

MAP Crosslinker Chirality Regulates Macrophage Polarization Through MD-2 Engagement and Enables Tunable Immunomodulation Through Novel Peptide Design. [PDF]

Adv Healthc Mater
Suarez-Arnedo A, Thomas JL, Liu Y, Cordero-Alvarado P, Kim A, Espinoza AC, Harvey L, Poysungnoen K, Lin F, Ye Z, Segura T.   +10 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Calycosin attenuates LPS-induced microglia inflammatory responses and microglia-mediated synaptic impairment via modulation of TLR4/MyD88/NF-κB signaling pathway. [PDF]

Front Pharmacol
Gao X, Wang R, Chen H, Chen X, Wang X.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source