Results 261 to 270 of about 262,724 (386)

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-κB Pathway

Drug Design, Development and Therapy
Yingxu Shi,1 Yu Tang,2 Zhiwei Sun,3 Ping Sui,4 Yiming Shao,4 Zhonghao Wang,4 Jian Zhang,1 Ming Gao1 1Department of Trauma Orthopedics, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272007, People’s Republic of China; 2Pharmaceutical
Shi Y, Tang Y, Sun Z, Sui P, Shao Y, Wang Z, Zhang J, Gao M   +7 more
doaj  

TLR4/MyD88 expression patterns and novel genetic variants: association with aggressive clinicopathological features in colorectal cancer. [PDF]

Front Oncol
Dang TT, Pham VN, Tran ND, Ngo TH, Can VM, Nguyen HH, Nguyen TX, Dang TC.   +7 more
europepmc   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

HMGB1 and TLR4 as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study. [PDF]

BMC Endocr Disord
Zhu G, Kan C, Cao C, Zhu H.
europepmc   +1 more source

SELECTIVE EXPRESSION OF HO-1 BY TISSUE Mø IN RESPONSE TO INFLAMMATION: THE ROLE OF TLR4 AND PROINFLAMMATORY CYTOKINES

, 2002
Xianzhong Meng, Yongyan Song, Lihua Ao, Alden H. Harken   +3 more
openalex   +1 more source

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source

Lactobacillus Protects Against Chronic Suppurative Otitis Media via Modulating RFTN1/ Lipid Raft /TLR4-Mediated Inflammation

Biologics: Targets & Therapy
Zhuohui Liu,* Fan Zhang,* Fengfeng Jia, Shuling Li, Chaowu Jiang, Biao Ruan, Ruiqing Long Department of Otolaryngology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, People’s Republic of China*These authors ...
Liu Z, Zhang F, Jia F, Li S, Jiang C, Ruan B, Long R   +6 more
doaj  

The Role of Myeloid Differentiation Factor 2 in Stroke: Mechanisms and Therapeutic Potential. [PDF]

Biomolecules
Zhu D, Zhao J, Chen Q, Liu Q, Fang Y.
europepmc   +1 more source

ENDOTOXIN (LPS) STIMULATES IN VIVO EXPRESSION OF INFLAMMATORY CYTOKINES IN SKELETAL MUSCLE VIA TLR4.

, 2002
Charles H. Lang, Christine Silvis, Gerald J. Nystrom, R A Frost   +3 more
openalex   +1 more source