Results 111 to 120 of about 16,392 (208)

Toward a porcine in vivo model to analyze the pathogenesis of TLR5-dependent enteropathies

Gut Microbes, 2020
Non-communicable diseases, such as the metabolic syndrome and inflammatory bowel disease, constitute serious public health threats in developed countries.
Robert Pieper, Niels van Best, Kira van Vorst, Friederike Ebner, Monika Reissmann, Mathias W. Hornef, Marcus Fulde   +6 more
doaj   +1 more source

mRNA levels of TLR4 and TLR5 are independent of H pylori

World Journal of Gastroenterology, 2008
To determine if the presence H pylori or its virulence affect toll-like receptor 4 (TLR4) and TLR5 mRNA expression levels.For the in vivo assays, gastric biopsies were obtained from 40 patients and H pylori status was determined. For the in vitro assays, human gastric adenocarcinoma mucosal cells (AGS) were cultured in the presence or absence of twelve
Garza González, Elvira, Bocanegra García, Virgilio, Bosques Padilla, Francisco Javier, Flores Gutiérrez, Juan Pablo, Moreno, Francisco, Perez Perez, Guillermo Ignacio   +5 more
openaire   +3 more sources

Impact of TLR5 and NAIP silencing on MUC5AC expression.

, 2012
NCI-H292 cells were transfected with TLR5 or Naip siRNA and then treated with or without purified flagellin (Flag, 1 µg/ml) for 24 h. Scrambled siRNA was used as a negative control for transfection. (A) Shows the effect of siRNA transfection on flagellin-
Viviane Balloy (17494), Michel Chignard (17499), Fatima Ben Mohamed (153382), Reuben Ramphal (153404), Mathieu Medina (153393), Lhousseine Touqui (74585), Ignacio Garcia-Verdugo (153387)   +6 more
core   +1 more source

TLR5: beyond the recognition of flagellin [PDF]

Cellular & Molecular Immunology, 2017
Jingyi, Yang, Huimin, Yan
openaire   +2 more sources

Gut microbiota influence B cell function in a TLR5-dependent manner

, 2019
Toll-like receptor (TLR) 5-deficient mice display aberrantly low levels of flagellin-specific antibodies (Flic-IgA) secreted into the gut, combined with excess bacterial flagellin in the gut, and together these attributes define microbiome dysbiosis (T5 ...
Li, S., Chassaing, B., Ley, R. ; https://orcid.org/, Walters, W., Zhang, B., Waters, J. ; https://orcid.org/, Leifer, C., Shi, Q., Gewirtz, A.   +8 more
core   +1 more source

Study of the regolatory role of TLR5 in the development of dendritic cells in type 1 diabetes

reservedTLR5 è un recettore transmembrana che riconosce la flagellina batterica ed è espresso in numerose cellule, tra cui le cellule dendritiche (DC).
CAMPAGNOLO, SERENA
core  

Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival

, 2013
Toll-like receptors (TLR) are overexpressed on many types of cancer cells, including colorectal cancer cells, but little is known about the functional relevance of these immune regulatory molecules in malignant settings.
Eckert, Jana, Bevier, Melanie, Hemminki, Kari, Hampe, Jochen, Weber, Alexander N. R., Heits, Nils, Hartl, Dominik, Foersti, Asta, Knezevic, Jelena, Walter, Jessica, von Schoenfels, Witigo, Hinz, Sebastian, Frick, Julia-Stefanie, Hemminki, Kari,, Lascorz, Jesus, Lund University., Klimosch, Sascha N., Schafmayer, Clemens   +17 more
core   +1 more source

Ligation of TLR5 promotes myeloid cell infiltration and differentiation into mature osteoclasts in rheumatoid arthritis and experimental arthritis

, 2015
Our aim was to examine the impact of TLR5 ligation in rheumatoid arthritis (RA) and experimental arthritis pathology. Studies were conducted to investigate the role of TLR5 ligation on RA and mouse myeloid cell chemotaxis or osteoclast formation, and in ...
Volkov, Suncica, Amin, M. Asif, Shahrara, Shiva, Swedler, William, Lane, Nancy E., Arami, Shiva, Chen, Zhenlong, Mehta, Anjali, Volin, Michael V., Essani, Abdul B., Sweiss, Nadera, Kim, Seung-Jae, Chamberlain, Nathan D., Gravallese, Ellen M.   +13 more
core   +1 more source

Expression and significance of Toll-like receptor 5 in peripheral blood mononuclear cells of patients with rheumatoid arthritis

Zhongguo linchuang yanjiu
Objective To examine the expression levels of Toll-like receptor 5 (TLR5) on peripheral blood monocytes in patients with rheumatoid arthritis (RA), and to explore its clinical significance.
ZHANG Wenxin, XIONG Jinhe
doaj   +1 more source

Ligation of TLR5 Promotes Myeloid Cell Infiltration and Differentiation into Mature Osteoclasts in Rheumatoid Arthritis and Experimental Arthritis

, 2014
Our aim was to examine the impact of TLR5 ligation in rheumatoid arthritis (RA) and experimental arthritis pathology. Studies were conducted to investigate the role of TLR5 ligation on RA and mouse myeloid cell chemotaxis or osteoclast formation, and in ...
Volkov, Suncica, Amin, M Asif, Shahrara, Shiva, Swedler, William, Gravallese, Ellen M, Arami, Shiva, Volin, Michael V, Chen, Zhenlong, Mehta, Anjali, Lane, Nancy E, Kim, Seung-jae, Essani, Abdul B, Sweiss, Nadera, Chamberlain, Nathan D   +13 more
core   +1 more source