Results 301 to 310 of about 148,110 (341)

In silico analyses on the comparative sensing of SARS‐CoV‐2 mRNA by the intracellular TLRs of humans

Journal of Medical Virology, 2021
The coronavirus disease‐2019 (COVID‐19) pandemic caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has already resulted in a huge setback to mankind in terms of millions of deaths, while the unavailability of an appropriate ...
Nabarun Chandra Das, Suprabhat Mukherjee, Ritwik Patra   +2 more
exaly   +2 more sources

Upregulated-gene expression of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) via TLRs following NF-κB and MAPKs in bovine mastitis

Acta Tropica, 2020
Mastitis is the inflammation of mammary glands which causes huge economic loss in dairy cows. Inflammation, any tissue injury and pathogens in cow udder activate Toll-like Receptors (TLRs). Staphylococcus aureus (S. aureus) is the major cause of mastitis.
Hua Zhang, Muhammad Akhtar, Shuai Guo
exaly   +2 more sources

The role of toll-like receptors (TLRs) in pan-cancer [PDF]

Annals of Medicine, 2022
Toll-like receptors (TLRs) are important components of the innate and adaptive immune systems, and abnormal TLR expression has been linked to a variety of cancers.
Tong Meng, Zongqiang Huang, Dianwen Song   +2 more
exaly   +4 more sources

TLRs/NLRs: Shaping the landscape of host immunity

International Reviews of Immunology, 2018
Gourango Pradhan, Sangita Mukhopadhyay
exaly   +2 more sources

Pattern recognition receptors in grass carp Ctenopharyngodon idella: I. Organization and expression analysis of TLRs and RLRs

Developmental and Comparative Immunology, 2017
Jianguo Su, Quanyuan Wan
exaly   +2 more sources

Viral proteins recognized by different TLRs

Journal of Medical Virology, 2021
Virus invasion activates the host's innate immune response, inducing the production of numerous cytokines and interferons to eliminate pathogens. Except for viral DNA/RNA, viral proteins are also targets of pattern recognition receptors.
Rui Zhou, Li Liu, Y. Wang
semanticscholar   +1 more source

TLR signalling and association of TLR polymorphism with cardiovascular diseases

Vascular Pharmacology, 2016
Toll-Like receptors (TLRs) are the primary receptors of innate immunity. Considerable evidences have shown that innate immune defence interaction with pro-inflammatory pathways could be through TLRs that in turn leads to development of inflammatory diseases. These TLRs are present on various tissues and cells of cardiovascular system.
Swati, Sharma, Iti, Garg, Mohammad Z, Ashraf   +2 more
openaire   +2 more sources

TLR signaling pathways

Seminars in Immunology, 2004
Toll-like receptors (TLRs) have been established to play an essential role in the activation of innate immunity by recognizing specific patterns of microbial components. TLR signaling pathways arise from intracytoplasmic TIR domains, which are conserved among all TLRs.
Kiyoshi, Takeda, Shizuo, Akira
openaire   +2 more sources

TLR based therapeutics

Current Opinion in Pharmacology, 2011
Toll-like receptors (TLRs) play a crucial role in innate immune responses to infection. Binding of agonists to TLRs promotes maturation of antigen presenting cells, such as dendritic cells, which in turn directs the induction of adaptive immune responses.
Aisling, Dunne, Neil A, Marshall, Kingston H G, Mills   +2 more
openaire   +2 more sources