Results 151 to 160 of about 25,778 (287)

Trimethylamine N-Oxide Improves Exercise Performance by Reducing Oxidative Stress through Activation of the Nrf2 Signaling Pathway

Molecules
Trimethylamine N-oxide (TMAO) has attracted interest because of its association with cardiovascular disease and diabetes, and evidence for the beneficial effects of TMAO is accumulating.
Hong Zou, Yu Zhou, Lijing Gong, Caihua Huang, Xi Liu, Ruohan Lu, Jingjing Yu, Zhenxing Kong, Yimin Zhang, Donghai Lin   +9 more
doaj   +1 more source

Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk [PDF]

, 2018
Xinmin S. Li, Zeneng Wang, Tomáš Čajka, Jennifer A. Buffa, Ina Nemet, Alex G. Hurd, Xiaodong Gu, Sarah M. Skye, Adam Roberts, Yuping Wu, Lin Li, Christopher J. Shahen, Matthew A. Wagner, Jaana Hartiala, Robert L. Kerby, Kymberleigh A. Romano, Yi Han, Slayman Obeid, Thomas F. Lüscher, Hooman Allayee, Federico E. Rey, Joseph A. DiDonato, Oliver Fiehn, W.H. Wilson Tang, Stanley L. Hazen   +24 more
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Trimethylamine-N-oxide and 5-year mortality: the role of gut microbiota-generated metabolite from the CORE-Thailand cohort

Scientific Reports
The gut microbiota metabolite trimethylamine-N-oxide (TMAO)—derived from dietary phosphatidylcholine—is mechanistically linked to cardiovascular disease (CVD) and increased cardiovascular risk.
Vichai Senthong, Songsak Kiatchoosakun, Chaiyasith Wongvipaporn, Jutarop Phetcharaburanin, Piyamitr Sritara, Arintaya Phrommintikul, CORE Investigators   +6 more
doaj   +1 more source

The microbial metabolite trimethylamine N-oxide and the kidney diseases

Frontiers in Cellular and Infection Microbiology
Trimethylamine N-oxide (TMAO), a metabolite, is a co-metabolite produced by both gut microbiota and livers, originating from foods rich in choline or carnitine.
Jin-Qi Su, Jin-Qi Su, Xiang-Qi Wu, Xiang-Qi Wu, Qi Wang, Qi Wang, Bo-Yang Xie, Bo-Yang Xie, Cui-Yan Xiao, Cui-Yan Xiao, Hong-Yong Su, Hong-Yong Su, Ji-Xin Tang, Ji-Xin Tang, Cui-Wei Yao, Cui-Wei Yao   +15 more
doaj   +1 more source

Nobiletin prevents TMAO-induced vascular oxidative stress in rats

, 2019
Guliang Yang, Chi‐Chen Lin, Yuan Li, Peilei Wang, Yiwen Yang, Xiang Wen, Hui Zhao, Chi‐Tang Ho, Shiming Li   +8 more
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Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans [PDF]

, 2016
Elko Randrianarisoa, Angela Lehn‐Stefan, Xiaolin Wang, Miriam Hoene, Andreas Peter, Silke S. Heinzmann, Xinjie Zhao, Ingmar Königsrainer, Alfred Königsrainer, Bernd Balletshofer, Jürgen Machann, Fritz Schick, Andreas Fritsche, Hans‐Ulrich Häring, Guowang Xu, Rainer Lehmann, Norbert Stefan   +16 more
openalex   +1 more source

Network and Experimental Pharmacology on Mechanism of Yixintai Regulates the TMAO/PKC/NF-κB Signaling Pathway in Treating Heart Failure

Drug Design, Development and Therapy
Ziyan Wang,1,2,* Chengxin Liu,1,2,* Jiaming Wei,2,3 Hui Yuan,1,2 Min Shi,2,3 Fei Zhang,2,3 Qinghua Zeng,2,3 Aisi Huang,2,3 Lixin Du,4 Ya Li,4 Zhihua Guo2,3 1First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine ...
Wang Z, Liu C, Wei J, Yuan H, Shi M, Zhang F, Zeng Q, Huang A, Du L, Li Y, Guo Z   +10 more
doaj  

Impact of the Healthy Lifestyle Community Program (HLCP-3) on Trimethylamine N-Oxide (TMAO) and Risk Profile Parameters Related to Lifestyle Diseases During the Six Months Following an Intervention Study [PDF]

Dima-Karam Nasereddin Alzughayyar, Ragna‐Marie Kranz, Sarah Husain, Nora Schoch, Heike Englert   +4 more
openalex   +1 more source

Dose-response meta-analysis of plasma TMAO and stroke: validated linear risk threshold at 3.0 μmol/L [PDF]

Jiakai Zhang, Tao Yu, Lefang Liu, Ruizhi Luan   +3 more
openalex   +1 more source

Gut microbiota‐derived metabolite trimethylamine N‐oxide aggravates cognitive dysfunction induced by femoral fracture operation in mice

Kaohsiung Journal of Medical Sciences
An increasing number of elderly individuals are experiencing postoperative cognitive dysfunction (POCD) problems after undergoing hip replacement surgery, with gut microbiota metabolites playing a role in its pathogenesis.
Ying Xiong, Ya‐Nan Pu, Li‐Ya Li, Yang Su, Jia‐Yuan Niu, Zhao‐Yang Xiao   +5 more
doaj   +1 more source