Results 181 to 190 of about 21,015 (212)

Gut microbiota metabolic reprogramming drives the development of metabolic diseases in the host. [PDF]

Gut Microbes
Wang Y, Huang B, Wei X, Guan Y, Li L, Zheng Y, Sun W.   +6 more
europepmc   +1 more source

Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5. [PDF]

Elife
Mahen KK, Massey WJ, Orabi D, Brown AL, Jaramillo TC, Burrows A, Horak AJ, Dutta S, Mrdjen M, Mouannes N, Varadharajan V, Osborn LJ, Ye X, Yarbrough DM, Grubb T, Zajczenko N, Hohe R, Banerjee R, Linga P, Laungani D, Hajjar AM, Sangwan N, Dwidar M, Buffa JA, Swanson GR, Wang Z, Brown JM.   +26 more
europepmc   +1 more source

Correlations Between Trimethylamine-N-Oxide, Megalin, Lysine and Markers of Tubular Damage in Chronic Kidney Disease. [PDF]

Toxins (Basel)
Kapetanaki S, Salihovic S, Kumawat AK, Massy ZA, Persson K, Barany P, Stenvinkel P, Evans M, Demirel I.   +8 more
europepmc   +1 more source

Gut microbiota-derived trimethylamine N-oxide exacerbates diabetic nephropathy by promoting renal fibrosis. [PDF]

World J Nephrol
Song YJ, Yang B, Feng QS, Ma FF, Xing B, Bin XL, Ha XQ.   +6 more
europepmc   +1 more source

Cardiovascular effects of trimethylamine N-oxide (TMAO)

, 2022
openaire   +1 more source

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Protein Stability in TMAO and Mixed Urea–TMAO Solutions

The Journal of Physical Chemistry B, 2020
Osmolytes are essential for cellular function under ubiquitous osmotic stress. Trimethylamine N-oxide (TMAO) is one such osmolyte that has gained remarkable attention due to its protein-protective ability against urea. This Review aims at providing a detailed account of recent theoretical and experimental developments in characterizing the structural ...
Pritam Ganguly, Jakub Polák, Nico F. A. van der Vegt, Jan Heyda, Joan-Emma Shea   +4 more
openaire   +4 more sources

Aqueous TMAO solution under high hydrostatic pressure

Physical Chemistry Chemical Physics, 2021
Aqueous TMAO solution in a diamond anvil cell pressurized up to 12 kbar shows spectral shifts in its THz extinction due to TMAO compression, increased TMAO–water coordination and a better visibility of hydration water around the hydrophobic groups.
Inga Kolling, Christoph Hölzl, Sho Imoto, Serena R. Alfarano, Hendrik Vondracek, Lukas Knake, Federico Sebastiani, Fabio Novelli, Claudius Hoberg, Jean-Blaise Brubach, Pascale Roy, Harald Forbert, Gerhard Schwaab, Dominik Marx, Martina Havenith   +14 more
openaire   +2 more sources

A bacterial TMAO transporter

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2002
Trimethylamine oxide (TMAO) acts as an osmolyte in a wide variety of marine organisms, but little is known about the mechanisms by which it accumulates in certain tissues. To determine whether a TMAO-specific transporter occurs in Nature, we examined a bacterium Aminobacter aminovorans that is known to be able to subsist on methylamine as the sole ...
James A, Raymond, George E, Plopper
openaire   +2 more sources