Results 21 to 30 of about 116,398 (271)

Structural elaboration of the surprising ortho-zincation of benzyl methyl ether [PDF]

open access: yes, 2010
Breaking with convention, the reaction of the sodium zincate, [(TMEDA)Na(μ-TMP)(μ-tBu)Zn(tBu)] with benzyl methyl ether (PhCH2OMe) produces exclusively an ortho-zincated intermediate [(TMEDA)Na(μ-TMP)(μ-C6H4CH2OMe)Zn(tBu)] instead of the expected ...
Alan R. Kennedy   +24 more
core   +1 more source

Development of Thin Films from Thermomechanical Pulp Nanofibers of Radiata Pine (Pinus radiata D. Don) for Applications in Bio-Based Nanocomposites

open access: yesFibers, 2022
The main objective of this study was to develop cellulose nanofibers from the thermomechanical pulp (TMP) of Radiata Pine (Pinus radiata D. Don), and for this, a one-step micro-grinding process was used.
Judith Vergara-Figueroa   +5 more
doaj   +1 more source

Production of tetra-methylpyrazine using engineered Corynebacterium glutamicum. [PDF]

open access: yes, 2020
Corynebacterium glutamicum ATCC 13032 is an established and industrially-relevant microbial host that has been utilized for the expression of many desirable bioproducts.
Chen, Yan   +8 more
core  

Fluid-structure interaction and flow redistribution in membrane-bounded channels [PDF]

open access: yes, 2019
The hydrodynamics of electrodialysis and reverse electrodialysis is commonly studied by neglecting membrane deformation caused by transmembrane pressure (TMP).
Battaglia G.   +6 more
core   +1 more source

A Faster Triphosphorylation Ribozyme. [PDF]

open access: yes, 2015
In support of the RNA world hypothesis, previous studies identified trimetaphosphate (Tmp) as a plausible energy source for RNA world organisms. In one of these studies, catalytic RNAs (ribozymes) that catalyze the triphosphorylation of RNA 5'-hydroxyl ...
Akoopie, Arvin   +2 more
core   +4 more sources

Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system

open access: yesAsian Journal of Pharmaceutical Sciences, 2019
In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine (TMP) is enhanced when combined with borneol (BN) in a microemulsion-based transdermal therapeutic system (ME-TTS).
Xiaoge Hu   +8 more
doaj   +1 more source

Underuse of statins for secondary prevention of atherosclerotic cardiovascular disease events among ambulatory surgical patients

open access: yesPreventive Medicine Reports, 2020
Although statins are highly effective for reducing cardiovascular disease events, prior studies demonstrate their significant underuse in the US population, including among those with known atherosclerotic disease.
Robert B. Schonberger   +10 more
doaj   +1 more source

Tetramethylpyrazine Preserves the Integrity of Blood-Brain Barrier Associated With Upregulation of MCPIP1 in a Murine Model of Focal Ischemic Stroke

open access: yesFrontiers in Pharmacology, 2021
Tetramethylpyrazine (TMP), a prominent ingredient of Chinese herb Ligusticum chuanxiong Hort, is known to suppress neuroinflammation and protect blood-brain barrier (BBB) integrity.
Zhuqing Jin   +3 more
doaj   +1 more source

Pharmacological plasticity—How do you hit a moving target?

open access: yesPharmacology Research & Perspectives, 2019
Paul Ehrlich's concept of the magic bullet, by which a single drug induces pharmacological effects by interacting with a single receptor has been a strong driving force in pharmacology for a century.
Michael J. Parnham, Gerd Geisslinger
doaj   +1 more source

Diisopropylamide and TMP turbo-grignard reagents : a structural rationale for their contrasting reactivities [PDF]

open access: yes, 2010
A neutral dimeric molecule in crystal form, the diisopropylamido turbo-Grignard reagent "(iPr2N)MgCl⋅LiCl" (see structure; blue N, red O, green Mg, yellow Cl, black C) separates into several charged ate species in dynamic exchange with each other in THF ...
Armstrong, David R.   +4 more
core   +1 more source

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