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Myeloid Activator Protein-1 Complex Contributes to Salt-Sensitive Hypertension. [PDF]

Circ Res
Ahmad T, Saleem M, Mutchler AP, Ertuglu LA, Sheng Q, Albritton CF, Haynes AP, Demirci M, Desta S, Khan MM, McMillan R, Afolabi J, Kirabo A.   +12 more
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A monoclonal antibody directed to Tn antigen

Biochemical and Biophysical Research Communications, 1990
A murine monoclonal antibody, MLS 128, that was assigned to an anti-Tn antibody has been established by immunizing mice with human colonic cancer cells (LS 180). MLS 128 bound to mucin glycopeptides from LS 180 cells and their asialo forms to the same extent as well as to ovine submaxillary mucin (OSM) and asialo OSM.
Y, Numata, H, Nakada, S, Fukui, H, Kitagawa, K, Ozaki, M, Inoue, T, Kawasaki, I, Funakoshi, I, Yamashina   +8 more
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An Example of Polyagglutinability Due to the Tn Antigen

British Journal of Haematology, 1970
Summary. A case of atypical polyagglutinability due to the Tn antigen is described. The patient, although apparently healthy, has leucopenia and thrombocytopenia. Her cells presented the usual difficulties of polyagglutinable cells due to the presence of anti‐Tn in typing reagents whether of human or animal origin.
H H, Gunson, F, Stratton, G W, Mullard
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Enzymatic synthesis of the Tn antigen

Journal of Molecular Catalysis B: Enzymatic, 2007
The enzymatic synthesis of the Tn antigen (GalNAc--O-Ser), a glyco-aminoacid of great biological importance, is reported. The reaction was promoted by commercial -N-acetylgalactosaminidase from Acremonium sp., using p-nitrophenyl--N-acetylgalactosamine as the donor. The kinetics were monitored by capillary electrophoresis and LC–UV-MS.
COSLOVI, ANNA, Cristiana Campa, FLAMIGNI, ANNA, Marco Rossi, VETERE, AMEDEO, Fulvio Uggeri, PAOLETTI, SERGIO   +6 more
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Tn and Sialyl‐Tn antigens in canine gastric tissues

Veterinary and Comparative Oncology, 2020
AbstractMalignant transformation is often associated with abnormal protein glycosylation expressed, amongst others, by the accumulation of simple mucin‐type carbohydrates namely Tn and Sialyl‐Tn (STn) antigens. These are usually limited in normal tissues and their increased expression has been associated with cancer progression and poor prognosis. This
Ana R. Flores, Isabel Lemos, Alexandra Rema, Marian Taulescu, Fernanda Seixas, Celso A. Reis, Fátima. Gärtner, Irina Amorim   +7 more
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Immunohistochemical detection of sialosyl‐Tn antigen in carcinoma of the prostate

British Journal of Urology, 1997
Objective  To investigate the expression of sialosyl‐Tn antigen (STn) in human benign and malignant prostate. Materials and methods  The expression of STn was investigated immunohistochemically in formalin‐fixed and paraffin‐embedded ...
H, Kuwabara, H, Uda, I, Takenaka
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Tissue Expression of Sialyl Tn Antigen in Gynecologic Tumors

Journal of Obstetrics and Gynaecology, 1995
AbstractObjective(s): To investigate tissue expression of Sialyl Tn antigen (STN) in gynecologic tumors, and to compare with its appearance in blood circulation.Methods: Surgical specimens were obtained from 24 patients with malignant gynecologic diseases, including 7 ovarian cancers, 13 cervical cancers, 3 endometrial cancers, and 1 vulval cancer ...
F, Numa, N, Tsunaga, T, Michioka, S, Nawata, H, Ogata, H, Kato   +5 more
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Immunohistochemical Evaluation of Sialosyl-Tn Antigens in Various Ovarian Carcinomas

Gynecologic Oncology, 1993
Sialosyl-Tn (S-Tn) antigen, a cancer-related antigen, was expressed in 56.3% (36 of 64 cases) of the common epithelial carcinoma tissues. This antigen was moderately to strongly expressed in 83.3% (15 of 18 cases) of the mucinous adenocarcinomas. In contrast, it was weakly expressed in 31.3% (5 of 16 cases) of the serous adenocarcinomas.
K, Ryuko, O, Iwanari, M, Kitao, S, Moriwaki   +3 more
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