Results 161 to 170 of about 621,791 (286)
CYP11B2 immunohistochemistry identifies aldosterone‐producing nodules and enables objective subtyping using the B2 ratio (B2R), defined as the size ratio between the largest and second‐largest CYP11B2‐positive nodules. A B2R ≥8.1 indicates classical histology with a dominant lesion and high likelihood of cure, whereas B2R <8.1 reflects non‐classical ...
Adam Stenman +3 more
wiley +1 more source
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti +9 more
wiley +1 more source
ABSTRACT Background Flow cytometry and real‐time quantitative polymerase chain reaction (qRT‐PCR) for MYD88 mutations (MYD88mt) are routinely performed on bone marrow aspirates during the diagnostic evaluation of IgM monoclonal paraproteinemia. The potential predictive value of immunophenotypic findings for molecular results, however, remains to be ...
Georgios Boutsikas +10 more
wiley +1 more source
Tn antigen suppresses lipopolysaccharide-induced dermatitis via Clec10a
C-type lectin domain family 10 member A (Clec10a), also called macrophage galactose-type lectin 1 (MGL1) or CD301a, is expressed on myeloid cells, including macrophages in the skin.
Kazuko Shibuya +13 more
core
The Leukocyte Landscape Across Mouse Strains and Tissues
The blood, bone marrow, liver, lymph nodes, and spleen of naïve male mice contained unique immunobiomes which differed between commonly used strains. BALB‐derived strains exhibited helper‐ and innate‐biased immune profiles, C57BL/6J‐derived strains were enriched for cytotoxic and immune surveillance populations, and DBA/2 J mice displayed elevated γδ T
Ella Trolio +4 more
wiley +1 more source
Development of a scalable synthesis of the Sialyl-Tn antigen
Amandeep Sehmbi Uwill abstract Development of a scalable synthesis of the Sialyl-Tn antigen Amandeep Sehmbi, Michael Reynolds, John F. Trant The sialyl-Tn antigen (sTn) is a naturally occurring carbohydrate commonly associated with epithelial cancers ...
Sehmbi, Amandeep
core +1 more source
ABSTRACT Background Durvalumab plus tremelimumab (Dur/Tre) has shown promising efficacy in advanced hepatocellular carcinoma (HCC), but predictive biomarkers remain unclear. This study aimed to determine whether early changes in peripheral blood lymphocyte counts during Dur/Tre therapy can predict clinical outcomes.
Yuichi Honma +36 more
wiley +1 more source
In adults with hematologic malignancies, RSV vaccination was safe and induced antibody and T‐cell responses. However, antibody levels were lower and declined more rapidly than in healthy controls. While early immune responses were evident, reduced magnitude and durability of protection suggest the need for optimized vaccination strategies in this high ...
Alisse Hannaford +32 more
wiley +1 more source
ABSTRACT Background Chikungunya virus (CHIKV) is an arbovirus that causes an acute febrile illness with intense muscle and joint pain, with the possibility of progressing to a chronic or neurological stage. We conducted a systematic review and meta‐analysis with the aim of evaluating the accuracy of real‐time reverse transcriptase polymerase chain ...
Róger J. Costa +8 more
wiley +1 more source

