Results 91 to 100 of about 51,359 (249)
Data for spatial transcriptomics on triple negative breast cancers The repository contains a number of (tarballed) directories. byArray - data by array/subarray classification - data relative to the classification / regression at the spot level, as well as the per-annotation gene expressions Clinical - clinical data and link array / samples ...
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Health Care Science, EarlyView.This study validates a novel Breast Modular Resection (BMR) teaching model for breast‐conserving surgery under regional anesthesia. The BMR approach significantly improves surgical proficiency, reduces re‐excision rates and pain, and facilitates safe day‐case discharge with superior cosmetic outcomes. ABSTRACT Background Breast‐conserving surgery (BCS)
Ru Yao +7 more
wiley +1 more source
De‐Escalation of Neoadjuvant Treatment for HER2‐Positive Breast Cancer
International Journal of Cancer, EarlyView.ABSTRACT With improved prognosis in early HER2‐positive breast cancer, safely de‐escalating treatment is increasingly investigated to minimize overtreatment. This article focuses on neoadjuvant de‐escalation strategies for HER2‐positive breast cancer.
Yiyin Ma, Dedian Chen, Sheng Huang
wiley +1 more source
Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival
International Journal of Cancer, EarlyView.ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li +10 more
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari +10 more
wiley +1 more source
We provide evidence here that a basic defining characteristic of the TNBC transcriptome in black women is high expression of the gene that encodes the human growth homolog gene, HGH1.
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Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer
International Journal of Cancer, EarlyView.ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue +6 more
wiley +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Multiomics Analysis of Gene Expression and Drug Sensitivity Relationship in Breast Cancer Subtypes
Online Academic Journal of Information TechnologyBreast cancer is a complex disease exhibiting distinct clinical behaviors due to its molecular heterogeneity. In this study, 30 breast cancer cell lines were categorized into two main analysis groups: 'Hormone/HER2 Positive' (n=12) and 'TNBC' (triple ...
Adem Sonuvar +2 more
doaj +1 more source