Results 101 to 110 of about 74,225 (263)

Insights into the Prognostic Value of Small Nucleolar RNA U81 and SNORA7B in Breast Cancer

International Journal of General Medicine, 2022
Jun Zhou,1 Xuan Zhu,2 Jingpei Long1 1Department of Breast Surgery, The Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Radiotherapy, The First Affiliated Hospital of Zhejiang ...
Zhou J, Zhu X, Long J
doaj  

TNBC grade 3 averaged spectra.

, 2022
EMSC-corrected 2nd derivative spectra of TNBC grade 3 breast tissue before (a) and after (b) preoperative chemotherapy with assigned minima.
Marian Cholewa (130937), Jitraporn Vongsvivut (2142607), Ewa Kaznowska (12219112), Izabela Zawlik (4585600), Magdalena Kołodziej (12219109), Sylwia Paszek (4585588), Józef Cebulski (12219115), Edyta Barnaś (3937382)   +7 more
core   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Prognostic Value of Vimentin in Triple Negative Breast Cancer Patients Depends on Chemotherapy Regimen and p53 Mutant Expression

Breast Cancer: Targets and Therapy, 2023
Ibnu Purwanto,1,* Benedreky Leo,2,* Susanna Hilda Hutajulu,1 Johan Kurnianda,1 Kartika Widayati Taroeno-Hariadi,1 Mardiah Suci Hardianti,1 Amanda Dania Satiti,1 Ery Kus Dwianingsih,3 Didik Setyo Heriyanto,3 Irianiwati Widodo,3 Teguh Aryandono4 ...
Purwanto I, Leo B, Hutajulu SH, Kurnianda J, Taroeno-Hariadi KW, Hardianti MS, Satiti AD, Dwianingsih EK, Heriyanto DS, Widodo I, Aryandono T   +10 more
doaj  

TNBC grade 2 averaged spectra.

, 2022
EMSC-corrected 2nd derivative spectra of TNBC grade 2 breast tissue before (a) and after (b) preoperative chemotherapy with assigned minima.
Marian Cholewa (130937), Jitraporn Vongsvivut (2142607), Ewa Kaznowska (12219112), Izabela Zawlik (4585600), Magdalena Kołodziej (12219109), Sylwia Paszek (4585588), Józef Cebulski (12219115), Edyta Barnaś (3937382)   +7 more
core   +1 more source

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

Advanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha, Jaehyun Kim, Seyoung Kim, Gonna Somu Naidu, Sungchan Cho, Seok‐Beom Yong   +5 more
wiley   +1 more source

Diagnosis of Triple Negative Breast Cancer (TNBC) Using Mammography [PDF]

, 2021
Triple-Negative Breast Cancer (TNBC) is a malignant, aggressive cancer that can affect men or women. Mammography is very helpful in diagnosing this type of cancer. The only option at this time for treatment for TNBC is cytotoxic chemotherapy.
Mihalka, Sarah
core  

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Plots of the patients with TNBC (left) and non-TNBC (right) illustrating the effect of including a texture parameter (HGRE) in addition to SUVmax for classification of breast cancer.

, 2014
In both tumor groups (TNBC and non-TNBC), adding HGRE to SUVmax improves the classification of the tumor if the patient is located above the diagonal. The probability of correct classification increased in 77% of TNBC (10/13) and in 71% (29/41) of non ...
Michael Soussan (550009), Marianne Ziol (550012), Fanny Orlhac (550010), Marouane Boubaya (550011), Véronique Eder (550013), Laurent Zelek (485038), Irène Buvat (550014)   +6 more
core   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source