Results 121 to 130 of about 74,225 (263)

Algorithm that shows the selection path of TNBC patients.

, 2019
Algorithm that shows the selection path of TNBC patients.
Kamran Alimoghaddam (827007), Maziar Pourkasmaee (6175580), Seied Asadollah Mousavi (6175577), Mohammad Vaezi (4427254), Ardeshir Ghavamzadeh (827006), Sahar Tavakoli (6175586), Amir Kasaeian (3161763), Hosein Kamranzadeh Fumani (4330231), Davoud Babakhani (6175583)   +8 more
core   +1 more source

AI‐Assisted Ultrasensitive Biosensing using Metal‐Electrolyte‐Metal‐Insulator‐Silicon Structure Based on Oxygen‐Tunable Iridium Oxide Nanonets for Lysyl‐Oxidase‐Like‐2 Breast Cancer Detection

Advanced Electronic Materials, EarlyView.
An oxygen‐controlled iridium‐oxide (IrOx) nano‐net structure is developed to enhance the sensitivity of metal‐electrolyte‐metal‐insulator‐silicon (MEMIS) biosensors. Integrated with a deep learning model, this platform achieves a high accuracy of 94.8% for detecting the breast cancer biomarker LOXL2.
Chiao‐Fan Chiu, Pankaj Kumar, Long Nguyen Minh Le, Ping‐Hsuan Wu, Punnatorn Boonyoung, Shen Tingyang, Abhijit Aich, Yi‐Pin Chen, Shih‐Yin Huang, Siddheswar Maikap   +9 more
wiley   +1 more source

Sensitivity of TNBC cell lines to DNA damaging agents.

, 2019
Sensitivity of TNBC cell lines to DNA damaging agents.
Joel F. Andrews (5340578), Zachary D. Nagel (7481030), Natalie R. Gassman (126331), Cortt G. Piett (7481024), Kevin J. Lee (3170862), Elise Mann (7481027)   +5 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Multiomics Analysis of Gene Expression and Drug Sensitivity Relationship in Breast Cancer Subtypes

Online Academic Journal of Information Technology
Breast cancer is a complex disease exhibiting distinct clinical behaviors due to its molecular heterogeneity. In this study, 30 breast cancer cell lines were categorized into two main analysis groups: 'Hormone/HER2 Positive' (n=12) and 'TNBC' (triple ...
Adem Sonuvar, Esra Tokur Sonuvar, Uğur Bilge   +2 more
doaj   +1 more source

Advances in siRNA Drug Delivery Strategies for Targeted TNBC Therapy

Among breast cancers, triple-negative breast cancer (TNBC) has been recognized as the most aggressive type with a poor prognosis and low survival rate.
Vladimir P. Torchilin, Md Abdus Subhan
core   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Cancer

Breast Cancer: Targets and Therapy
Ponkrit Kaewkedsri,1 Piyapharom Intarawichian,1 Sirawich Jessadapattarakul,1 Waritta Kunprom,1 Supinda Koonmee,1 Malinee Thanee,1 Ongart Somintara,2 Anongporn Wongbuddha,2 Payia Chadbunchachai,3 Supajit Nawapun,3 Chaiwat Aphivatanasiri1 1Department of ...
Kaewkedsri P, Intarawichian P, Jessadapattarakul S, Kunprom W, Koonmee S, Thanee M, Somintara O, Wongbuddha A, Chadbunchachai P, Nawapun S, Aphivatanasiri C   +10 more
doaj  

Quinoxaline amino derivatives as potential EGFR-targeted therapeutics in breast cancer: computational exploration

Journal of Applied Pharmaceutical Research
Background: Despite resistance to current tyrosine kinase inhibitors, which makes the epidermal growth factor receptor (EGFR) a recognized therapeutic target in breast cancer, there is a need for novel inhibitors.
Abitha H, D. Kumudha, Bhuvaneswari Sivaraman, M. K. Kathiravan   +3 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source