Results 11 to 20 of about 565,658 (299)
Indonesia Journal of Biomedical Science, 2012 Painful Diabetic Neuropathy (PDN) is one of the most common and annoyingcomplications of diabetes mellitus. The pathogenesis of PDN is complex and still unclear.Recently it has become clear that nitric oxide (NO) and proinflammatory cytokines playan important role in the pathogenesis and maintenance of pain in PDN.
Thomas Eko Purwata +3 more
openaire +1 more source
Impact of TNF-α Inhibitors on Body Weight and BMI: A Systematic Review and Meta-Analysis
Frontiers in Pharmacology, 2020 ObjectiveThe aim of this systematic review and meta-analysis of longitudinal studies was to ascertain to effects of TNF-α inhibitor therapy on body weight and BMI.MethodsThree databases (PubMed, OVID, and EMBASE) were systematically searched from ...
Olivia Patsalos +4 more
doaj +1 more source
Critical role of tumor necrosis factor-α in the early process of wound healing in skin
Journal of Dermatology and Dermatologic Surgery, 2017 Tumor necrosis factor (TNF)-α is quickly released and initiates inflammation at wound tissues, but its precise role in wound healing is not fully understood.
Masae Ritsu +7 more
doaj +1 more source
Inhibition of Akt phosphorylation attenuates resistance to TNF-α cytotoxic effects in MCF-7 cells, but not in their doxorubicin resistant derivatives [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of ...
Morteza Ghandadi +6 more
doaj +1 more source
TNF‐α polymorphisms affect persistence and progression of HBV infection
Molecular Genetics & Genomic Medicine, 2019 Background Hepatitis B virus (HBV) infections are a major threat worldwide. Disease progression and outcome is diverse and depends on host genetic background. Recently, a high rate of HBV reactivation in individuals receiving tumor necrosis factor‐α (TNF‐
Anna Woziwodzka +6 more
doaj +1 more source
Neurobiology of Disease, 2009 TNF-α has been reported to be relevant in stroke-induced neuronal death. However the precise function of TNF-α in brain ischemia remains controversial since there are data supporting either a detrimental or a protective effect. Here we show that TNF-α is
Nahuai Badiola +6 more
doaj +1 more source
Frontiers in Immunology, 2021 BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has infected over 112M patients and resulted in almost 2.5M deaths worldwide.
Esmaeil Mortaz +15 more
doaj +1 more source
TNF-α Differentially Regulates Cell Cycle Genes in Promyelocytic and Granulocytic HL-60/S4 Cells
G3: Genes, Genomes, Genetics, 2019 Tumor necrosis factor alpha (TNF-α) is a potent cytokine involved in systemic inflammation and immune modulation. Signaling responses that involve TNF-α are context dependent and capable of stimulating pathways promoting both cell death and survival. TNF-
Elsie C. Jacobson +6 more
doaj +1 more source
Physiological Reports, 2021 Intravenous infusion of relatively higher doses of angiotensin II (AngII) elicits natriuresis as opposed to its usual anti‐natruretic response. As AngII can induce tumor necrosis factor‐α (TNFα) production which elicits natriuresis via its action on TNFα
Dewan S. A. Majid, Alexander Castillo
doaj +1 more source
TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China. [PDF]
PLoS ONE, 2017 Tumor necrosis factor-α (TNF-α), an important factor in systematic inflammation, is reportedly involved in several cancer types. The TNF-α -308 G>A (rs1800629) polymorphism in the promoter region influences TNF-α production. The association between TNF-α
Zhen Li +11 more
doaj +1 more source