Results 41 to 50 of about 565,658 (299)

Pengaruh Antosianin Ubi Ungu terhadap TNF-α, Apoptosis dan Memori Spasial Hipokampus Tikus Model Diabetes Melitus

Jurnal Kedokteran Brawijaya, 2018
Hiperglikemia pada diabetes melitus menyebabkan penurunan fungsi memori spasial. Terapi yang efektif terhadap gangguan fungsi kognitif akibat hiperglikemia yang sampai saat ini masih dalam perdebatan, menjadikan pendekatan pencegahan menjadi pilihan.
Darwatik Darwatik, Retty Ratnawati, Sri Rianawati, Imam Sarwono   +3 more
openaire   +2 more sources

Estudo de polimorfismos genéticos do HLA (classes I e II) e do TNF-α em doentes com sarcoidose

Revista Portuguesa de Pneumologia, 2008
Resumo: Introdução: A susceptibilidade genética na ocorrência da sarcoidose é sugerida por alguns factores, nomeadamente pela observação de casos de agregação familiar e a associação da raça a diferentes tipos de incidência e gravidade da doença.
António Morais, Helena Alves, Bruno Lima, Luís Delgado, Ricardo Gonçalves, Sandra Tafulo   +5 more
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

THE ROLE OF IFN- γ AND TNF- α IN EXPERIMENTAL MASTITIS

The Iraqi Journal of Agricultural science, 2021
This study was design to characterize the immune response in experimentally Pseudomonas aeruginosa mastitis mice treated probiotic bifidocin and cazacin of Bifidobacterium spp. and Lactobacillus casei.
Touma & et al
doaj  

Hubungan antara Kadar Tumor Necrosis Factor-Alpha (TNF-α) Plasma dengan Kejang Demam Sederhana pada Anak

Jurnal Kedokteran Brawijaya, 2014
Kejang demam adalah penyebab kejang paling umum pada anak dan sering menjadi penyebab rawat inap di rumah sakit secara darurat. Studi pendahuluan pada anak menunjukkan bahwa jaringan sitokin diaktifkan dan mungkin berperan dalam patogenesis kejang demam namun, signifikansi klinis yang tepat masih belum jelas.
Dewi Nurindah, Masdar Muid, Sumarno Retoprawiro   +2 more
openaire   +2 more sources

ORAL INTAKE OF SARDINELLA LONGICEPS OIL THE DECREASE OF TNF-α AND IL-6 LEVELS IN ATHEROSCLEROTIC WISTAR RAT

Indonesia Journal of Biomedical Science, 2012
Lifestyle changes to consumption of variegated instant food may be associated several heath hazards, such as obesity, dyslipidemia, and atheroschlerosis. This study was conducted to investigate the effects of orally administered Sardinella longiceps oil as an anti inflammatory agent on the serum levels of TNF-α and IL-6 considered as biomarkers for ...
S. Wahjuni, A.A.G. Sudewa, I Wayan Wita, I.N. Mantik Astawa   +3 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1.

PLoS ONE, 2014
Eosinophils play a central role in asthma. The present study was performed to investigate the effect of tumour necrosis factor-α (TNF-α) on longevity of isolated human eosinophils.
Hannu Kankaanranta, Pinja Ilmarinen, Xianzhi Zhang, Ian M Adcock, Aleksi Lahti, Peter J Barnes, Mark A Giembycz, Mark A Lindsay, Eeva Moilanen   +8 more
doaj   +1 more source

Pengaruh Ekstrak Metanol Biji Mahoni terhadap Peningkatan Kadar Insulin, Penurunan Ekspresi TNF-αdan Perbaikan Jaringan Pankreas Tikus Diabetes

Jurnal Kedokteran Brawijaya, 2013
Diabetes mellitus(DM) merupakan penyakit gangguan metabolisme yang ditandai dengan meningkatnya kadar glukosa darah  (hiperglikemia)  akibat  gangguan  sekresi  insulin  dan  atau  meningkatnya  resistensi  insulin.  T erapi  ekstrak  metanol  biji mahoni (Swetenia  mahagoni Jacq)  merupakan  salah  satu  pengobatan  alternatif  ...
Nany Suryani, Tinny Endang H, Aulanni'am Aulanni'am   +2 more
openaire   +2 more sources

The expression of TNF-α, IL-1β, and IL-10 in the diabetes mellitus condition induced by the combination of spirulina and chitosan

Bali Medical Journal, 2020
Background: Rapid wound healing is needed after tooth extraction treatment so that prosthodontics treatment can be done immediately. However, systemic diseases, such as diabetes mellitus, can inhibit the wound healing process. The state of hyperglycemia in people with diabetes mellitus can interfere with the function of macrophages and neutrophils ...
Nike Hendrijantini, -, Ratri Maya Sitalaksmi, -, Muhammad Dimas Aditya Ari, -, Tiffany Josephine Hidayat, -, Prisca Agustina Nurcahyani Putri, -, Daniel Sukandar, -   +5 more
openaire   +1 more source