Results 31 to 40 of about 1,312 (166)

Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2014
BackgroundRhinella schneideri, previously known as Bufo paracnemis, is a common toad in many regions of Brazil. Its venom exerts important cardiovascular effects on humans and other animals.
Sandro Rostelato-Ferreira   +4 more
doaj   +1 more source

Bufalin suppresses ovarian cancer cell proliferation via EGFR pathway

open access: yesChinese Medical Journal, 2022
. Background:. Previous studies have shown that bufalin exerts antitumor effects through various mechanisms. This study aimed to determine the antineoplastic mechanism of bufalin, an extract of traditional Chinese medicine toad venom, in ovarian cancer ...
Lei Dou   +7 more
doaj   +1 more source

Research progress in the anti-cancer activity and related mechanisms of arenobufagin

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban
Toad venom is an active extract of toad, which is processed by distilling or drying at high temperature the venom secreted from the skin glands and ear-side glands of Toad Chinensis.
BAI Wenhui, SHEN Shukun, WU Yingli
doaj   +1 more source

Dosagem de marcadores cardíacos CK-MB e TnIc e eletrólitos no envenenamento experimental por veneno de sapo em cães

open access: yesPesquisa Veterinária Brasileira, 2009
Dentre os sinais sistêmicos causados pelo envenenamento por veneno de sapo (bufotoxina) em cães, os efeitos cardiotóxicos são um dos mais importantes. O objetivo deste estudo foi avaliar as potenciais alterações no músculo cardíaco de cães envenenados ...
Annelise C. Camplesi   +3 more
doaj   +1 more source

Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells. [PDF]

open access: yesPLoS ONE, 2016
Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough.
Qingxi Yue   +9 more
doaj   +1 more source

Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi

open access: yesMolecules, 2021
Toads in the family Bufonidae contain bufadienolides in their venom, which are characterized by their chemical diversity and high pharmacological potential.
Candelario Rodriguez   +6 more
doaj   +1 more source

Resibufogenin and cinobufagin activate central neurons through an ouabain-like action. [PDF]

open access: yesPLoS ONE, 2014
Cinobufagin and resibufogenin are two major effective bufadienolides of Chan su (toad venom), which is a Chinese medicine obtained from the skin venom gland of toads and is used as a cardiotonic and central nervous system (CNS) respiratory agent, an ...
Ze-Jun Wang   +2 more
doaj   +1 more source

Studies on Toad Venom (3): Effect of Metals on the Quality of Toad Venom Torrefied on a Metal Plate

open access: yesYAKUGAKU ZASSHI, 2002
To study the quality of toad venom dried on different metal plates by heating at 105 degrees C, each 20 g sample of fresh toad venom collected in Hei-Long-Jiang Province, China, was dried on (1) brass, (2) copper, (3) glass, (4) acrylic resins, (5) aluminum and (6) stainless-steel, respectively.
Kazuhito, Kawahara, Masayuki, Mikage
openaire   +3 more sources

The impacts of biological invasions

open access: yesBiological Reviews, EarlyView.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock   +42 more
wiley   +1 more source

A neuro‐behavioural model of neophobia

open access: yesBiological Reviews, EarlyView.
ABSTRACT Fear can be defined as the internal neurological state that releases a repertoire of behaviours an animal performs to reduce the effect of an aversive factor. Neophobia, the fear of novelty, is a fundamental behavioural trait observed across a wide range of species from arthropods to humans.
Arik Dorfman, Aziz Subach, Inon Scharf
wiley   +1 more source

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