Results 101 to 110 of about 22,677 (265)

First Phase of Glucose-Stimulated Insulin Secretion From MIN 6 Cells Does Not Always Require Extracellular Calcium Influx

open access: yesJournal of Pharmacological Sciences, 2006
.: To demonstrate an involvement of ATP-sensitive potassium (KATP) channel-independent pathways in the first phase of glucose-stimulated insulin secretion (GSIS) from pancreatic β cells, the time course of GSIS from MIN6 cells was analyzed at 30-s sample
Shigeto Makoto   +4 more
doaj   +1 more source

Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats

open access: yesDrug Design, Development and Therapy, 2021
Yong Shi,1,* Deru Meng,1,* Shuanghu Wang,1 Peiwu Geng,1 Tao Xu,2 Quan Zhou,1 Yunfang Zhou,1 Wanshu Li,3 Xugao Chen4 1Comprehensive Breast Health Center, Department of Thyroid and Breast Surgery, The Sixth Affiliated Hospital of Wenzhou Medical ...
Shi Y   +8 more
doaj  

Treatment of Diabetes With Oral Hypoglycemic Drugs [PDF]

open access: yes, 1966
Oral hypoglycemic drugs now available are of two types. The biguanides, of which phenformin (DBI) is the only one available, increase glucose utilization by muscles.
Moss, James M.
core   +1 more source

Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine’s Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P450 2C9 Enzymes

open access: yesPharmaceutics
Carbamazepine (CBZ) is commonly prescribed for epilepsy and frequently used in polypharmacy. However, concerns arise regarding its ability to induce the metabolism of other drugs, including itself, potentially leading to the undertreatment of co ...
Xuefen Yin   +5 more
doaj   +1 more source

Oral Hypoglycemic Agents [PDF]

open access: yes, 1977
In conclusion, comment is made on the findings of the University Group Diabetes Program (UGDP). The purpose of the UGDP was to determine whether or not control of blood glucose levels would help to prevent or delay vascular disease in non-insulin ...
Rifkin, Harold
core   +1 more source

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