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Frontiers in Cellular and Infection Microbiology, 2022 BackgroundEnterobacter bugandensis is an emerging human pathogen in which multidrug resistant strains have been continuously isolated from various environments. Thus, this organism possesses the potential to pose challenges in human healthcare.
Bingyu Li +3 more
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Sensors, 2021 Animal behavior is an essential element in behavioral neuroscience study. However, most behavior studies in small animals such as fruit flies (Drosophila melanogaster) have been performed in a limited spatial chamber or by tethering the fly’s body on a ...
Pikam Pun +4 more
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PLoS ONE, 2022 Fatty acids salts exhibit bacteriostatic and bactericidal effects to inhibit bacterial growth and survival. Bacteria adapt to their environment to overcome these antibacterial effects through undefined mechanisms.
Tomohiro Yoneda +4 more
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The Colicin E1 TolC Box: Identification of a Domain Required for Colicin E1 Cytotoxicity and TolC Binding [PDF]
Journal of Bacteriology, 2017 ABSTRACT Colicins are protein toxins made by Escherichia coli to kill related bacteria that compete for scarce resources. All colicins must cross the target cell outer membrane in order to reach their intracellular targets.
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Kinetic control of TolC recruitment by multidrug efflux complexes [PDF]
Proceedings of the National Academy of Sciences, 2009 In Gram-negative pathogens, multidrug efflux pumps that provide clinically significant levels of antibiotic resistance function as three-component complexes. They are composed of the inner membrane transporters belonging to one of three superfamilies of proteins, RND, ABC, or MF; periplasmic proteins belonging to the membrane fusion ...
Elena B, Tikhonova +3 more
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Kanamycin-Mediated Conformational Dynamics of Escherichia coli Outer Membrane Protein TolC
Frontiers in Molecular Biosciences, 2021 TolC is a member of the outer membrane efflux proteins (OEPs) family and acts as an exit duct to export proteins, antibiotics, and substrate molecules across the Escherichia coli cell membrane.
Biraja S. Pattanayak +6 more
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TolC Affects Virulence Gene Expression in Vibrio cholerae [PDF]
Journal of Bacteriology, 2011 A Vibrio cholerae tolC mutant showed increased toxT expression in M9 medium, but not in the presence of four amino acids that induce cholera toxin production, and in LB with high osmolarity but not high pH or temperature. TolC did not affect expression of other regulatory genes in the ToxR regulon.
Yusuke, Minato +2 more
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Frontiers in Microbiology, 2011 TolC is an archetypal member of the Outer membrane Efflux Protein (OEP) family. These proteins are involved in export of peptide and small molecule toxins across the outer membrane of Gram-negative bacteria.
Helen I. Zgurskaya +3 more
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Absence of TolC Impairs Biofilm Formation in Actinobacillus pleuropneumoniae by Reducing Initial Attachment. [PDF]
PLoS ONE, 2016 Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a major cause of economic loss in swine industry worldwide.
Ying Li +11 more
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TolC-Dependent Exclusion of Porphyrins in Escherichia coli [PDF]
Journal of Bacteriology, 2008 ABSTRACT We found that Escherichia coli tolC mutants showed increased sensitivity to 5-aminolevulinic acid (ALA), a precursor of porphyrins. The tolC mutant cells grown in the presence of ALA showed a reddish brown color under visible light and a strong red fluorescence under near ...
Tatsumi, R., Wachi, M.
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