Results 31 to 40 of about 7,251 (175)
Journal of Pure and Applied Microbiology, 2022 AcrAB-TolC is a resistance nodulation division type of efflux pump present in Enterobacteriaceae. It non-specifically effluxes antibiotics out of the bacterial cell, thus conferring drug resistance.
Priyadharshini Sekar +3 more
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TolC – the bacterial exit duct for proteins and drugs [PDF]
FEBS Letters, 2003 The TolC structure has unveiled a common mechanism for the movement of molecules, large and small, from the bacterial cell cytosol, across two membranes and the intervening periplasm, into the environment. Trimeric TolC is a remarkable cell exit duct that differs radically from other membrane proteins, comprising a 100‐Å long α‐barrel that projects ...
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Biocide Selective TolC-Independent Efflux Pumps in Enterobacteriaceae [PDF]
The Journal of Membrane Biology, 2017 Bacterial resistance to biocides used as antiseptics, dyes, and disinfectants is a growing concern in food preparation, agricultural, consumer manufacturing, and health care industries, particularly among Gram-negative Enterobacteriaceae, some of the most common community and healthcare-acquired bacterial pathogens.
Slipski, Carmine J. +2 more
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Molecular Plant-Microbe Interactions, 2008 Sinorhizobium meliloti is capable of establishing a symbiotic nitrogen fixation relationship with Medicago sativa. During this process, it must cope with diverse environments and has evolved different types of transport systems that help its propagation ...
Ana M. Cosme +5 more
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Microorganisms, 2022 Biofilm formation is a survival strategy by which microorganisms adapt to environmental challenges. It is regulated by various signals, such as the second messenger c-di-GMP. We previously found that the Flm chemosensory pathway could respond to chemical
Yunhao Wang +6 more
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JDS Communications, 2021 Nitric oxide (NO) is a biological signal molecule that can control and prevent the growth of most pathogens. Cronobacter species are a group of gram-negative foodborne pathogens that cause severe diseases, including neonatal meningitis, septicemia, and ...
Dengyu Liu +7 more
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PLoS ONE, 2009 Pneumonia associated with Iegionnaires's disease is initiated in humans after inhalation of contaminated aerosols. In the environment, Legionella pneumophila is thought to survive and multiply as an intracellular parasite within free-living amoeba.
Mourad Ferhat +5 more
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Transition to the open state of the TolC periplasmic tunnel entrance [PDF]
Proceedings of the National Academy of Sciences, 2002 The TolC channel-tunnel spans the bacterial outer membrane and periplasm, providing a large exit duct for protein export and multidrug efflux when recruited by substrate-engaged inner membrane complexes. The sole constriction in the single pore of the homotrimeric TolC is the periplasmic tunnel entrance, which in its resting configuration is closed by ...
Christian, Andersen +6 more
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Functional Implications of an Intermeshing Cogwheel-like Interaction between TolC and MacA in the Action of Macrolide-specific Efflux Pump MacAB-TolC [PDF]
Journal of Biological Chemistry, 2011 Macrolide-specific efflux pump MacAB-TolC has been identified in diverse gram-negative bacteria including Escherichia coli. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein MacA to form a functional tripartite complex.
Yongbin, Xu +11 more
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BMC Microbiology, 2010 Background The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa.
Moreira Leonilde M +5 more
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