Results 111 to 120 of about 10,453,112 (207)

Plain Language Summary on Scientific opinion on the tolerable upper intake level for manganese. [PDF]

EFSA J, 2023
europepmc   +1 more source

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Salt intake and iodine status around the world [PDF]

Background: Salt reduction and universal salt iodisation programmes are implemented worldwide to prevent cardiovascular disease and iodine deficiency disorders, respectively.
Ji, Chen (Researcher in medicine)
core  

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Contribution of fortified foods and dietary supplements to total nutrient intakes and their adequacy in Japanese adults

BMC Nutrition
Background This study examined how fortified foods and dietary supplements contributed to total nutrient intakes and their adequacy in Japanese adults. Methods Nutrient intake was estimated from 4-day dietary records of 392 adults (20–69 years) in total ...
Minami Sugimoto, Keiko Asakura, Nana Shinozaki, Kentaro Murakami, Shizuko Masayasu, Satoshi Sasaki   +5 more
doaj   +1 more source

Are low tolerable upper intake levels for vitamin a undermining effective food fortification efforts? [PDF]

, 2017
Vitamin A deficiency (VAD) is a major health problem, particularly in low-resource countries, putting an estimated 125-130 million preschool-aged children at increased risk of morbidity and mortality from infectious diseases.
Waelti, Monika, Moench-Pfanner, Regina, Hathcock, John N., Kraemer, Klaus, Semba, Richard D., de Pee, Saskia, Bloem, Martin W.   +6 more
core  

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Exposure‐Based Toxicological Evaluation of Lead and Elemental Impurities in Encapsulated Green Tea Dietary Supplements Under a Regulatory Framework

Journal of Applied Toxicology, EarlyView.
ABSTRACT The consumption of green tea (Camellia sinensis (L.) Kuntze) in the form of encapsulated dietary supplements has increased substantially in recent years; however, data supporting toxicological risk assessment of inorganic contaminants in these products remain limited.
Amanda da Silva Chaves, Lisia Maria Gobbo dos Santos, Beatriz Scaramelo, Júlia Maria Peixoto Loureiro, Fabio Coelho Amendoeira, Silvana do Couto Jacob, Fausto Klabund Ferraris   +6 more
wiley   +1 more source

Utilisation of Objective and Subjective Image Quality Metrics to Guide Optimal Contrast Volumes for Abdominal CT

Journal of Medical Radiation Sciences, EarlyView.
Determining the appropriate volume of iodinated contrast media (ICM) for portal venous phase abdominal CT is challenging. Objective image quality assessment demonstrates weight‐based volume dosing reduces the dependence of enhancement on patient size, compared to fixed volume.
Deborah Carrick, Mitchell Ashton, Joshua Bognar, Natalia Diaz, James Rogers, Daniel Serra, Daniel Schick   +6 more
wiley   +1 more source