Results 101 to 110 of about 9,068 (239)

Zinc Toxicity: Understanding the Limits

open access: yesMolecules
Zinc, a vital trace element, holds significant importance in numerous physiological processes within the body. It participates in over 300 enzymatic reactions, metabolic functions, regulation of gene expression, apoptosis and immune modulation, thereby ...
Hannah Schoofs   +2 more
doaj   +1 more source

When Is Improvement Possible? A Necessity‐Based Analysis of Short‐Term Eating Disorder Symptom Improvement During Inpatient Treatment

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating‐disorder–specific functional impairment may represent a boundary condition for treatment response, yet this possibility has rarely been examined. We investigated whether baseline functional impairment constrains short‐term eating‐disorder symptom improvement, indexed by change in EDE‐Q Global scores during inpatient treatment ...
Paolo Meneguzzo, Patrizia Todisco
wiley   +1 more source

Bio‐Inspired Robust Non‐combustible Bioplastic with Superinsulated Energy Harvesting for Intelligent Firefighting

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study develops a novel non‐combustible chitosan‐based bioplastic (NCCB) via ethanol‐induced surface assembly. The material's inherent flame retardancy and thermally insulating, rough surface enable high‐performance TENGs. The NCCB‐TENG maintains stable output even when exposed to fire and exhibits dual sensitivity to temperature (25–200°C) and ...
Qilin Lu   +5 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Modeling the Contribution of Multiple Micronutrient Fortification of Salt to Daily Nutrient Intake Among the Ethiopian Population

open access: yesCurrent Developments in Nutrition
Background: Salt is an affordable commodity and has wide coverage regardless of economic and social status and, hence, could be suitable vehicle for multiple micronutrient fortification.
Semira Mitiku Saje   +6 more
doaj   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Salt intake and iodine status around the world [PDF]

open access: yes
Background: Salt reduction and universal salt iodisation programmes are implemented worldwide to prevent cardiovascular disease and iodine deficiency disorders, respectively.
Ji, Chen (Researcher in medicine)
core  

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