Results 51 to 60 of about 3,251,457 (326)

Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells

open access: yesiScience, 2022
Summary: Pregnancy stimulates an intricately coordinated assortment of physiological changes to accommodate growth of the developing fetus, while simultaneously averting rejection of genetically foreign fetal cells and tissues.
Ashley L. Severance   +9 more
doaj   +1 more source

Robust state estimation using mixed integer programming [PDF]

open access: yes, 2008
This letter describes a robust state estimator based on the solution of a mixed integer program. A tolerance range is associated with each measurement and an estimate is chosen to maximize the number of estimated measurements that remain within tolerance
Irving, MR
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Increased tolerance to humans among disturbed wildlife. [PDF]

open access: yes, 2015
Human disturbance drives the decline of many species, both directly and indirectly. Nonetheless, some species do particularly well around humans. One mechanism that may explain coexistence is the degree to which a species tolerates human disturbance ...
Blumstein, Daniel T   +4 more
core   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Identification of Markers Associated with Wheat Dwarf Virus (WDV) Tolerance/Resistance in Barley (Hordeum vulgare ssp. vulgare) Using Genome-Wide Association Studies

open access: yesViruses, 2023
Wheat dwarf virus (WDV) causes an important vector transmitted virus disease, which leads to significant yield losses in barley production. Due to the fact that, at the moment, no plant protection products are approved to combat the vector Psammotettix ...
Behnaz Soleimani   +6 more
doaj   +1 more source

Development of a new scale to measure ambiguity tolerance in veterinary students [PDF]

open access: yes, 2017
The ability to cope with ambiguity and feelings of uncertainty is an essential element of professional practice. Research with physicians has identified that intolerance of ambiguity or uncertainty is linked to stress and some authors have hypothesised ...
Hammond, Jennifer A.   +4 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Loss of Zbtb32 in NOD mice does not significantly alter T cell responses. [version 1; referees: 2 approved]

open access: yesF1000Research, 2018
Background: We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes.
William D. Coley   +6 more
doaj   +1 more source

Ischemic Tolerance [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 1997
A brief period of cerebral ischemia confers transient tolerance to a subsequent ischemic challenge in the brain. This phenomenon of ischemic tolerance has been confirmed in various animal models of forebrain ischemia and focal cerebral ischemia. Since the ischemic tolerance afforded by preceding ischemia can bring about robust protection of the brain ...
openaire   +3 more sources

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