Results 41 to 50 of about 202,194 (309)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Visual tolerance analysis for engineering optimization
International Journal of Metrology and Quality Engineering, 2013 Classic methodologies of DOE are widely applied in design, manufacture, quality management and related fields. The resulting data can be analysed with linear modeling methods such as multiple regression which generates a set of ...
Zhou Wei W., Moore M., Kussener F.
doaj +1 more source
Software safety : a definition and some preliminary thoughts [PDF]
, 1981 Software safety is the subject of a research project in its initial stages at the University of California Irvine. This research deals with critical real-time software where the cost of an error is high, e.g. human life. In this paper software techniques
Leveson, Nancy G.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Formal proofs for broadcast algorithms [PDF]
, 2014 Standard distributed algorithmic solutions to recurring distributed problems are commonly specified and described informally. A proper understanding of these distributed algorithms that clarifies ambiguities requires formal descriptions.
Francalanza, Adrian, Zammit, Mandy
core +1 more source
Nanoparticle Platforms for Antigen-Specific Immune Tolerance [PDF]
Frontiers in Immunology, 2020 Innovative approaches in nanoparticle design have facilitated the creation of new formulations of nanoparticles that are capable of selectively calibrating the immune response. These nanomaterials may be engineered to interact with specific cellular and molecular targets.
Edward B. Thorp +4 more
openaire +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Financial risk tolerance within couples of retail bank clients
International Review of Economics & FinanceThis paper examines gender differences in spouses’ financial risk tolerance in a large sample of 10,231 couples of retail bank clients. Our measure of risk tolerance is self-assessed at the bank, in the presence of a financial advisor, through a ...
Marie-Hélène Broihanne, Hava Orkut
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Asian Development ReviewWhile economic inequality has gained prominence in the contemporary development debate, the reasons why the degree of tolerance for inequality varies among countries remain an unresolved issue. This knowledge gap has resulted in excessive policy emphasis
WANNAPHONG DURONGKAVEROJ
doaj +1 more source