Results 191 to 200 of about 4,982,676 (293)
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
MedComm, Volume 7, Issue 9, September 2026.Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
MedComm, Volume 7, Issue 9, September 2026.Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Tolerogenic functions in human autologous tolerogenic dendritic cells (ATDC)
Fonctions tolérantes dans les cellules dendritiques tolérogènes autologues humaines (ATDC) Notre étude aborde la question cruciale du rejet de greffe dans la transplantation rénale, où les médicaments immunosuppresseurs actuels présentent des risques significatifs.
openaire +2 more sources
Bifidobacterium bifidum, Akkermansia muciniphila and their extracellular vesicles induce tolerogenic dendritic cells in patients with Crohn’s disease [PDF]
Maryam Farmani +7 more
openalex +1 more source
Applications of Mesenchymal Stromal Cells for Treatment of Diseases
MedComm, Volume 7, Issue 9, September 2026.This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
MedComm, Volume 7, Issue 9, September 2026.This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source